Chapter 11
Multifunctional Graphene-Based Nanocomposites for Cancer Diagnosis and Therapy
Ayuob Aghanejad,
Parinaz Abdollahiyan,
Jaleh Barar,
Yadollah Omidi,
Ayuob Aghanejad
Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Iran
Search for more papers by this authorParinaz Abdollahiyan
Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Iran
Search for more papers by this authorJaleh Barar
Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Iran
Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Iran
Search for more papers by this authorYadollah Omidi
Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Iran
Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Iran
Search for more papers by this authorAyuob Aghanejad,
Parinaz Abdollahiyan,
Jaleh Barar,
Yadollah Omidi,
Ayuob Aghanejad
Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Iran
Search for more papers by this authorParinaz Abdollahiyan
Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Iran
Search for more papers by this authorJaleh Barar
Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Iran
Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Iran
Search for more papers by this authorYadollah Omidi
Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Iran
Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Iran
Search for more papers by this authorBook Editor(s):Yuen Yung Hui,
Huan-Cheng Chang,
Haifeng Dong,
Xueji Zhang,
Yuen Yung Hui
Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei, Republic of China
Search for more papers by this authorHuan-Cheng Chang
Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei, Republic of China
Search for more papers by this authorHaifeng Dong
University of Science and Technology Beijing, P.R. China
Search for more papers by this authorXueji Zhang
University of Science and Technology Beijing, P.R. China
Search for more papers by this authorSummary
Currently, the most common methods of cancer diagnosis include different imaging modalities such as single-photon emission computed tomography (SPECT), positron emission tomography (PET), computed tomography (CT), magnetic resonance imaging (MRI), and mammography. Gold nanoparticles (GNPs) and magnetic nanoparticles (MNPs) offer significant prospective tools for the targeted imaging and therapy of cancer. Polymeric nanocomposites (NCs) have been developed using various types of NPs and widely used for the cancer therapy. Polymeric nanohybrids can be harnessed to improve the biocompatibility and multi-responsiveness of drug delivery systems (DDSs) in the cancer therapy. By far, several studies have been carried out to implement different strategies to enhance and improve the photoconversion efficiency of such advanced nanobiomaterials to serve as probes for the early detection of cancer biomarkers in biological fluids of patients. Combination therapy using graphene and its derivatives have widely been extended, resulting in the production of new generation of multimodal pharmaceuticals.
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