Primary Cutaneous Lymphoma
Rebecca Levy
University of Toronto, The Hospital for Sick Children, Toronto, Canada
Search for more papers by this authorElena Pope
Section of Dermatology, Division of Pediatric Medicine, The Hospital for Sick Children, Toronto, Canada
Search for more papers by this authorRebecca Levy
University of Toronto, The Hospital for Sick Children, Toronto, Canada
Search for more papers by this authorElena Pope
Section of Dermatology, Division of Pediatric Medicine, The Hospital for Sick Children, Toronto, Canada
Search for more papers by this authorPeter Hoeger
Search for more papers by this authorVeronica Kinsler
Search for more papers by this authorAlbert Yan
Search for more papers by this authorJohn Harper
Search for more papers by this authorArnold Oranje
Search for more papers by this authorChristine Bodemer
Search for more papers by this authorMargarita Larralde
Search for more papers by this authorVibhu Mendiratta
Search for more papers by this authorDiana Purvis
Search for more papers by this authorSummary
The term ‘primary cutaneous lymphoma’ (PCL) refers to cutaneous lymphomas that present in the skin with no evidence of extracutaneous disease at the time of diagnosis. PCL is rare in children, comprising 5% of all cases. PCL is classified into three primary groups: cutaneous T-cell lymphomas (CTCL); cutaneous B-cell lymphomas (CBCL); and precursor haematological neoplasm. CTCL are the most common, accounting for 80% of childhood-onset PCL. Mycosis fungoides (MF) is the most common form of CTCL, with an overrepresentation of hypopigmented variants in the paediatric population. MF has been labelled ‘the great imitator’, illustrating the protean clinical manifestations of the disease; delays to diagnosis are therefore common. Paediatric survival in MF is usually excellent, as studies have consistently shown presentation in early-stage disease. Treatment modalities include phototherapy and topical corticosteroids, amongst other strategies. Other subtypes of primary cutaneous lymphoma are exceedingly rare in the paediatric population, but have been reported to varying degrees in the literature.
References
- Willemze R, Jaffe ES, Burg G et al. WHO-EORTC classification for cutaneous lymphomas. Blood 2005; 105(10): 3768–85.
- Bradford PT, Devesa SS, Anderson WF, Toro JR. Cutaneous lymphoma incidence patterns in the United States: a population-based study of 3884 cases. Blood 2009; 113(21): 5064–73.
- Wain EM, Orchard GE, Whittaker SJ et al. Outcome in 34 patients with juvenile-onset mycosis fungoides: a clinical, immunophenotypic, and molecular study. Cancer 2003; 98(10): 2282–90.
- Crowley JJ, Nikko A, Varghese A et al. Mycosis fungoides in young patients: clinical characteristics and outcome. J Am Acad Dermatol 1998; 38(5 Pt 1): 696–701.
- Olsen E, Vonderheid E, Pimpinelli N et al. Revisions to the staging and classification of mycosis fungoides and Sezary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous lymphoma task force of the European Organization of Research and Treatment of Cancer (EORTC). Blood 2007; 110(6): 1713–22.
- Kim YH, Willemze R, Pimpinelli N et al. TNM classification system for primary cutaneous lymphomas other than mycosis fungoides and Sezary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the Cutaneous Lymphoma Task Force of the European Organization of Research and Treatment of Cancer (EORTC). Blood 2007; 110(2): 479–84.
- Korgavkar K, Xiong M, Weinstock M. Changing incidence trends of cutaneous T-cell lymphoma. JAMA Dermatol 2013; 149(11): 1295–9.
- Peters MS, Thibodeau SN, White JW, Winkelmann RK. Mycosis fungoides in children and adolescents. J Am Acad Dermatol 1990; 22(6 Pt 1): 1011–18.
- Zackheim HS, McCalmont TH, Deanovic FW, Odom RB. Mycosis fungoides with onset before 20 years of age. J Am Acad Dermatol 1997; 36(4): 557–62.
- Van Doorn R, van Haselen CW, van Voorst Vader PC et al. Mycosis fungoides: disease evolution and prognosis of 309 Dutch patients. Arch Dermatol 2000; 136(4): 504–10.
- Boulos S, Vaid R, Aladily TN et al. Clinical presentation, immunopathology, and treatment of juvenile-onset mycosis fungoides: a case series of 34 patients. J Am Acad Dermatol 2014; 71(6): 1117–26.
- Koch SE, Zackheim HS, Williams ML et al. Mycosis fungoides beginning in childhood and adolescence. J Am Acad Dermatol 1987; 17(4): 563–70.
- Senerchia AA, Ribeiro KB, Rodriguez-Galindo C. Trends in incidence of primary cutaneous malignancies in children, adolescents, and young adults: a population-based study. Pediatr Blood Cancer 2014; 61(2): 211–16.
- Wain EM, Setterfield J, Judge MR et al. Mycosis fungoides involving the oral mucosa in a child. Clin Exp Dermatol 2003; 28(5): 499–501.
- Fink-Puches R, Chott A, Ardigó M et al. The spectrum of cutaneous lymphomas in patients less than 20 years of age. Pediatr Dermatol 2004; 21(5): 525–33.
- Zackheim HS. Cutaneous T cell lymphoma: update of treatment. Dermatology 1999; 199(2): 102–5.
- Tsianakas A, Kienast AK, Hoeger PH. Infantile-onset cutaneous T-cell lymphoma. Br J Dermatol 2008; 159(6): 1338–41.
- Tan E, Tay YK, Giam YC. Profile and outcome of childhood mycosis fungoides in Singapore. Pediatr Dermatol 2000; 17(5): 352–6.
- Pope E, Weitzman S, Ngan B et al. Mycosis fungoides in the pediatric population: report from an international Childhood Registry of Cutaneous Lymphoma. J Cutan Med Surg 2010; 14(1): 1–6.
- Amin A, Burkhart C, Groben P, Morrell DS. Primary cutaneous T-cell lymphoma following organ transplantation in a 16-year-old boy. Pediatr Dermatol 2009; 26(1): 112–13.
- Zackheim HS, McCalmont TH. Mycosis fungoides: the great imitator. J Am Acad Dermatol 2002; 47(6): 914–18.
- Zackheim HS. Treatment of mycosis fungoides/Sezary syndrome: the University of California, San Francisco (UCSF) approach. Int J Dermatol 2003; 42(1): 53–6.
- Pimpinelli N, Olsen EA, Santucci M et al. Defining early mycosis fungoides. J Am Acad Dermatol 2005; 53(6): 1053–63.
- Nanda A, Al Saleh QA, Al-Ajmi H et al. Mycosis fungoides in Arab children and adolescents: a report of 36 patients from Kuwait. Pediatr Dermatol 2010; 27(6): 607–13.
- Yazganoglu KD, Topkarci Z, Buyukbabani N, Baykal C. Childhood mycosis fungoides: a report of 20 cases from Turkey. J Eur Acad Dermatol Venereol 2011; 27(3): 295–300.
- Kim ST, Sim HJ, Jeon YS, et al. Clinicopathological features and T-cell receptor gene rearrangement findings of mycosis fungoides in patients younger than age 20 years. J Dermatol 2009; 36(7): 392–402.
- Hodak E, Amitay-Laish I, Feinmesser M et al. Juvenile mycosis fungoides: cutaneous T-cell lymphoma with frequent follicular involvement. J Am Acad Dermatol 2014; 70(6): 993–1001.
- Quaglino P, Zaccagna A, Verrone A et al. Mycosis fungoides in patients under 20 years of age: report of 7 cases, review of the literature and study of the clinical course. Dermatology 1999; 199(1): 8–14.
- Neuhaus IM, Ramos-Caro FA, Hassanein AM. Hypopigmented mycosis fungoides in childhood and adolescence. Pediatr Dermatol 2000; 17(5): 403–6.
- Ben-Amitai D, Michael D, Feinmesser M, Hodak E. Juvenile mycosis fungoides diagnosed before 18 years of age. Acta Derm Venereol 2003; 83(6): 451–6.
- Werner B, Brown S, Ackerman AB. ‘Hypopigmented mycosis fungoides’ is not always mycosis fungoides! Am J Dermatopathol 2005; 27(1): 56–67.
- Liu V, McKee PH. Cutaneous T-cell lymphoproliferative disorders: approach for the surgical pathologist: recent advances and clarification of confused issues. Adv Anat Pathol 2002; 9(2): 79–100.
- Smoller BR, Santucci M, Wood GS, Whittaker SJ. Histopathology and genetics of cutaneous T-cell lymphoma. Hematol Oncol Clin North Am 2003; 17(6): 1277–311.
- Smoller BR, Detwiler SP, Kohler S et al. Role of histology in providing prognostic information in mycosis fungoides. J Cutan Pathol 1998; 25(6): 311–15.
- Dalton SR, Chandler WM, Abuzeid M et al. Eosinophils in mycosis fungoides: an uncommon finding in the patch and plaque stages. Am J Dermatopathol 2012; 34(6): 586–91.
- Sanchez JL, Ackerman AB. The patch stage of mycosis fungoides. Criteria for histologic diagnosis. Am J Dermatopathol 1979; 1(1): 5–26.
- Massone C, Kodama K, Kerl H, Cerroni L. Histopathologic features of early (patch) lesions of mycosis fungoides: a morphologic study on 745 biopsy specimens from 427 patients. Am J Surg Pathol 2005; 29(4): 550–60.
- Nickoloff BJ. Light-microscopic assessment of 100 patients with patch/plaque-stage mycosis fungoides. Am J Dermatopathol 1988; 10(6): 469–77.
- Horiuchi Y, Tone T, Umezawa A, Takezaki S. Large cell mycosis fungoides at the tumor stage. Unusual T8, T4, T6 phenotypic expression. Am J Dermatopathol 1988; 10(1): 54–8.
- Cerroni L, Rieger E, Hödl S, Kerl H. Clinicopathologic and immunologic features associated with transformation of mycosis fungoides to large-cell lymphoma. Am J Surg Pathol 1992; 16(6): 543–52.
- Salhany K, Cousar J, Greer J et al. Transformation of cutaneous T cell lymphoma to large cell lymphoma. A clinicopathologic and immunologic study. Am J Pathol 1988; 132(2): 265–77.
- Vergier B, de Muret A, Beylot-Barry M et al. Transformation of mycosis fungoides: clinicopathological and prognostic features of 45 cases. French Study Group of Cutaneous Lymphomas. Blood 2000; 95(7): 2212–18.
- Diamandidou E, Colome-Grimmer M, Fayad L et al. Transformation of mycosis fungoides/Sezary syndrome: clinical characteristics and prognosis. Blood 1998; 92(4): 1150–9.
- Hsi AC, Lee SJ, Rosman IS et al. Expression of helper T cell master regulators in inflammatory dermatoses and primary cutaneous T-cell lymphomas: diagnostic implications. J Am Acad Dermatol 2015; 72(1): 159–67.
- Agnarsson B, Vonderheid E, Kadin M. Cutaneous T cell lymphoma with suppressor/cytotoxic (CD8) phenotype: identification of rapidly progressive and chronic subtypes. J Am Dermatol 1990; 22(4): 569–77.
- Berti E, Tomasini D, Vermeer MH et al. Primary cutaneous CD8-positive epidermotropic cytotoxic T cell lymphomas. A distinct clinicopathological entity with an aggressive clinical behavior. Am J Pathol 1999; 155(2): 483–92.
- Whittam L, Calonje E, Orchard G et al. CD8-positive juvenile onset mycosis fungoides: an immunohistochemical and genotypic analysis of six cases. Br J Dermatol 2000; 143(6): 1199–204.
- Lu D, Patel KA, Duvic M, Jones D. Clinical and pathological spectrum of CD8-positive cutaneous T-cell lymphomas. J Cutan Pathol 2002; 29(8): 465–72.
- El-Shabrawi-Caelen L, Cerroni L, Medeiros LJ, McCalmont TH. Hypopigmented mycosis fungoides: frequent expression of a CD8+ T-cell phenotype. Am J Surg Pathol 2002; 26(4): 450–7.
- Castano E, Glick S, Wolgast L et al. Hypopigmented mycosis fungoides in childhood and adolescence: a long-term retrospective study. J Cutan Pathol 2013; 40(11): 924–34.
- Cho-Vega J, Tschen J, Duvic M, Vega F. Early-stage mycosis fungoides variants: case-based review. Ann Diagn Pathol 2010; 14(5): 369–85.
- Hodak E, David M, Maron L et al. CD4/CD8 double-negative epidermotropic cutaneous T-cell lymphoma: an immunohistochemical variant of mycosis fungoides. J Am Acad Dermatol 2006; 55(2): 276–84.
- Santucci M, Pimpinelli N, Massi D et al. Cytotoxic/natural killer cell cutaneous lymphomas. Report of EORTC Cutaneous Lymphoma Task Force Workshop. Cancer 2003; 97(3): 610–27.
- Ohshima A, Tokura Y, Misawa J et al. Erythrodermic cutaneous T-cell lymphoma with CD8+CD56+ leukaemic T cells in a young woman. Br J Dermatol 2003; 149(4): 891–3.
- Wain EM, Orchard GE, Mayou S et al. Mycosis fungoides with a CD56+ immunophenotype. J Am Acad Dermatol 2005; 53(1): 158–63.
- Hagen JW, Schaefer JT, Magro CM. CD20+ mycosis fungoides: a report of three cases and review of the literature. Am J Dermatopathol 2013; 35(8): 833–41.
- Massone C, Crisman G, Kerl H, Cerroni L. The prognosis of early mycosis fungoides is not influenced by phenotype and T-cell clonality. Br J Dermatol 2008; 159(4): 881–6.
- Desai M, Liu S, Parker S. Clinical characteristics, prognostic factors, and survival of 393 patients with mycosis fungoides and Sézary syndrome in the southeastern United States: a single-institution cohort. J Am Acad Dermatol 2015; 72(2): 276–85.
- Fung MA, Murphy MJ, Hoss DM, Grant-Kels JM. Practical evaluation and management of cutaneous lymphoma. J Am Acad Dermatol 2002; 46(3): 325–57; quiz 358–60.
- Apisarnthanarax N, Talpur R, Ward S et al. Tazarotene 0.1% gel for refractory mycosis fungoides lesions: an open-label pilot study. J Am Acad Dermatol 2004; 50(4): 600–7.
- De Quatrebarbes J, Estève E, Bagot M et al. Treatment of early-stage mycosis fungoides with twice-weekly applications of mechlorethamine and topical corticosteroids: a prospective study. Arch Dermatol Am Med Assoc 2005; 141(9): 1117–20.
- Deeths MJ, Chapman JT, Dellavalle RP et al. Treatment of patch and plaque stage mycosis fungoides with imiquimod 5% cream. J Am Acad Dermatol 2005; 52(2): 275–80.
- Ramsay DL, Meller JA, Zackheim HS. Topical treatment of early cutaneous T-cell lymphoma. Hematol Oncol Clin North Am 1995; 9(5): 1031–56.
- Zackheim HS. Topical carmustine (BCNU) for patch/plaque mycosis fungoides. Semin Dermatol 1994; 13(3): 202–6.
- Zackheim HS, Kashani-Sabet M, Amin S. Topical corticosteroids for mycosis fungoides. Experience in 79 patients. Arch Dermatol 1998; 134(8): 949–54.
- Rook AH, Wood GS, Duvic M et al. A phase II placebo-controlled study of photodynamic therapy with topical hypericin and visible light irradiation in the treatment of cutaneous T-cell lymphoma and psoriasis. J Am Acad Dermatol 2010; 63(6): 984–90.
- Koh MJ-A, Chong W-S. Narrow-band ultraviolet B phototherapy for mycosis fungoides in children. Clin Exp Dermatol 2014; 39(4): 474–8.
- Laws PM, Shear NH, Pope E. Childhood mycosis fungoides: experience of 28 patients and response to phototherapy. Pediatr Dermatol 2014; 31(4): 459–64.
- Kanokrungsee S, Rajatanavin N, Rutnin S, Vachiramon V. Efficacy of narrowband ultraviolet B twice weekly for hypopigmented mycosis fungoides in Asians. Clin Exp Dermatol 2012; 37(2): 149–52.
- Jaffe ES. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. Geneva: IARC, 2001.
- Van Doorn R, Scheffer E, Willemze R. Follicular mycosis fungoides, a distinct disease entity with or without associated follicular mucinosis: a clinicopathologic and follow-up study of 51 patients. Arch Dermatol 2002; 138(2): 191–8.
- Hess Schmid M, Dummer R, Kempf W et al. Mycosis fungoides with mucinosis follicularis in childhood. Dermatology 1999; 198(3): 284–7.
- Gibson LE, Muller SA, Peters MS. Follicular mucinosis of childhood and adolescence. Pediatr Dermatol 1988; 5(4): 231–5.
- Spence-Shishido A, Streicher JL, George RP et al. Folliculotropic mycosis fungoides as a posttransplant lymphoproliferative disorder. Pediatrics 2015; 136(3): e701–5.
- Flaig MJ, Cerroni L, Schuhmann K et al. Follicular mycosis fungoides. A histopathologic analysis of nine cases. J Cutan Pathol 2001; 28(10): 525–30.
- Bonta MD, Tannous ZS, Demierre MF et al. Rapidly progressing mycosis fungoides presenting as follicular mucinosis. J Am Acad Dermatol 2000; 43(4): 635–40.
- Cohen EL. Woringer–Kolopp disease (pagetoid reticulosis). Clin Exp Dermatol 1978; 3(4): 447–50.
- Jones RR, Chu A. Pagetoid reticulosis and solitary mycosis fungoides. Distinct clinicopathological entities. J Cutan Pathol 1981; 8(1): 40–51.
- Mandojana RM, Helwig EB. Localized epidermotropic reticulosis (Woringer–Kolopp disease). J Am Acad Dermatol 1983; 8(6): 813–29.
- Mendese GW, Beckford A, Krejci N et al. Pagetoid reticulosis in a prepubescent boy successfully treated with photodynamic therapy. Clin Exp Dermatol 2012; 37(7): 759–61.
- Kempf W, Kazakov DV, Belousova IE et al. Paediatric cutaneous lymphomas: a review and comparison with adult counterparts. J Eur Acad Dermatol Venereol 2015; 29: 1696–709.
- Matsuzaki Y, Kimura K, Nakano H et al. Localized pagetoid reticulosis (Woringer–Kolopp disease) in early childhood. J Am Acad Dermatol 2009; 61(1): 120–3.
- Miedler JD, Kristjansson AK, Gould J et al. Pagetoid reticulosis in a 5-year-old boy. J Am Acad Dermatol 2008; 58(4): 679–81.
- MacDonald DM. Pagetoid reticulosis – is it a disease entity? Br J Dermatol 1982; 107(5): 603–4.
- Haghighi B, Smoller BR, LeBoit PE et al. Pagetoid reticulosis (Woringer–Kolopp disease): an immunophenotypic, molecular, and clinicopathologic study. Mod Pathol 2000; 13(5): 502–10.
- Mielke V, Wolff HH, Winzer M, Sterry W. Localized and disseminated pagetoid reticulosis. Diagnostic immunophenotypical findings. Arch Dermatol 1989; 125(3): 402–6.
- Burns MK, Chan LS, Cooper KD. Woringer–Kolopp disease (localized pagetoid reticulosis) or unilesional mycosis fungoides? An analysis of eight cases with benign disease. Arch Dermatol 1995; 131(3): 325–9.
- LeBoit PE. Granulomatous slack skin. Dermatol Clin 1994; 12(2): 375–89.
- Tsang WY, Chan JK, Loo KT et al. Granulomatous slack skin. Histopathology 1994; 25(1): 49–55.
- Noto G, Pravatà G, Miceli S, Aricò M. Granulomatous slack skin: report of a case associated with Hodgkin's disease and a review of the literature. Br J Dermatol 1994; 131(2): 275–9.
- LeBoit PE, Beckstead JH, Bond B et al. Granulomatous slack skin: clonal rearrangement of the T-cell receptor beta gene is evidence for the lymphoproliferative nature of a cutaneous elastolytic disorder. J Invest Dermatol 1987; 89(2): 183–6.
- Convit J, Kerdel F, Goihman M et al. Progressive, atrophying, chronic granulomatous dermohypodermitis. Autoimmune disease? Arch Dermatol 1973; 107(2): 271–4.
- Helm K, Cerio R, Winkelmann R. Granulomatous slack skin: a clinicopathological and immunohistochemical study of three cases. Br J Dermatol 1992; 126(2): 142–7.
- Camacho FM, Burg G, Moreno JC et al. Granulomatous slack skin in childhood. Pediatr Dermatol 1997; 14(3): 204–8.
- Sheng Y, Chen L, Huang Z et al. Granulomatous slack skin: assessment of disease progression and treatment response using positron emission tomography/computed tomography. Clin Lymphoma Myeloma 2009; 9(6): 455–8.
- DeGregorio R, Fenske NA, Glass LF. Granulomatous slack skin: a possible precursor of Hodgkin's disease. J Am Acad Dermatol 1995; 33(6): 1044–7.
- Clarijs M, Poot F, Laka A et al. Granulomatous slack skin: treatment with extensive surgery and review of the literature. Dermatology 2003; 206(4): 393–7.
- Ryan C, Whittaker S, d'Arcy C et al. Juvenile folliculotropic and ichthyosiform mycosis fungoides. Clin Exp Dermatol 2009; 34(5): e160–2.
- Hodak E, Amitay I, Feinmesser M et al. Ichthyosiform mycosis fungoides: an atypical variant of cutaneous T-cell lymphoma. J Am Acad Dermatol 2004; 50(3): 368–74.
- Meister L, Duarte AM, Davis J et al. Sézary syndrome in an 11-year-old girl. J Am Acad Dermatol 1993; 28(1): 93–5.
- LeBoit PE, Abel EA, Cleary ML et al. Clonal rearrangement of the T cell receptor beta gene in the circulating lymphocytes of erythrodermic follicular mucinosis. Blood 1988; 71(5): 1329–33.
- Setoyama M, Katahira Y, Kanzaki T. Clinicopathologic analysis of 124 cases of adult T-cell leukemia/lymphoma with cutaneous manifestations: the smouldering type with skin manifestations has a poorer prognosis than previously thought. J Dermatol 1999; 26(12): 785–90.
- DiCaudo DJ, Perniciaro C, Worrell JT et al. Clinical and histologic spectrum of human T-cell lymphotropic virus type I-associated lymphoma involving the skin. J Am Dermatol 1996; 34(1): 69–76.
- Nicot C. Current views in HTLV-I-associated adult T-cell leukemia/lymphoma. Am J Hematol. 2005; 78(3): 232–9.
- Yamaguchi T, Ohshima K, Karube K et al. Clinicopathological features of cutaneous lesions of adult T-cell leukaemia/ lymphoma. Br J Dermatol 2005; 152(1): 76–81.
- Uchiyama T, Yodoi J, Sagawa K. Adult T-cell leukemia: clinical and hematologic features of 16 cases. Blood 1977; 50(3): 481–92.
- Lin BT, Musset M, Székely AM et al. Human T-cell lymphotropic virus-1-positive T-cell leukemia/lymphoma in a child. Report of a case and review of the literature. Arch Pathol Lab Med 1997; 121(12): 1282–6.
-
Bittencourt AL, Primo J, Oliveira MFP. Manifestations of the human T-cell lymphotropic virus type I infection in childhood and adolescence. J Pediatr 2006; 82(6): 411–20.
10.2223/JPED.1573 Google Scholar
- Lucas CT, Gillis KJ, Ness JM et al. Adult T-cell leukemia/lymphoma in an adolescent presenting with skin lesions. Pediatr Dermatol 2008; 25(3): 373–7.
- Shimoyama M. Diagnostic criteria and classification of clinical subtypes of adult T-cell leukaemia-lymphoma. A report from the Lymphoma Study Group (1984-87). Br J Haematol 1991; 79(3): 428–37.
- Bittencourt AL, Barbosa HS, Vieira MDG, Farré L. Adult T-cell leukemia/lymphoma (ATL) presenting in the skin: clinical, histological and immunohistochemical features of 52 cases. Acta Oncol 2009; 48(4): 598–604.
- Willemze R, Beljaards RC. Spectrum of primary cutaneous CD30 (Ki-1)-positive lymphoproliferative disorders. A proposal for classification and guidelines for management and treatment. J Am Acad Dermatol 1993; 28(6): 973–80.
- Magro CM, Crowson AN, Kovatich AJ, Burns F. Drug-induced reversible lymphoid dyscrasia: a clonal lymphomatoid dermatitis of memory and activated T cells. Hum Pathol 2003; 34(2): 119–29.
- Kennedy MK, Willis CR, Armitage RJ. Deciphering CD30 ligand biology and its role in humoral immunity. Immunology 2006; 118(2): 143–52.
- Kumar S, Pittaluga S, Raffeld M et al. Primary cutaneous CD30-positive anaplastic large cell lymphoma in childhood: report of 4 cases and review of the literature. Pediatr Dev Pathol 2005; 8(1): 52–60.
- De Bruin PC, Beljaards RC, van Heerde P et al. Differences in clinical behaviour and immunophenotype between primary cutaneous and primary nodal anaplastic large cell lymphoma of T-cell or null cell phenotype. Histopathology 1993; 23(2): 127–35.
- Bekkenk MW, Geelen FA, van Voorst Vader PC et al. Primary and secondary cutaneous CD30(+) lymphoproliferative disorders: a report from the Dutch Cutaneous Lymphoma Group on the long-term follow-up data of 219 patients and guidelines for diagnosis and treatment. Blood 2000; 95(12): 3653–61.
- Hazneci E, Aydin NE, Dogan G, Turhan IO. Primary cutaneous anaplastic large cell lymphoma in a young girl. J Eur Acad Dermatol Venereol 2001; 15(4): 366–7.
- Tomaszewski MM, Moad JC, Lupton GP. Primary cutaneous Ki-1(CD30) positive anaplastic large cell lymphoma in childhood. J Am Acad Dermatol 1999; 40(5 Pt 2): 857–61.
-
Beljaards RC, Kaudewitz P, Berti E et al. Primary cutaneous CD30-positive large cell lymphoma: definition of a new type of cutaneous lymphoma with a favorable prognosis. A European multicenter study of 47 patients. Cancer 1993; 71(6): 2097–104.
10.1002/1097-0142(19930315)71:6<2097::AID-CNCR2820710626>3.0.CO;2-7 CAS PubMed Web of Science® Google Scholar
- Gould JW, Eppes RB, Gilliam AC et al. Solitary primary cutaneous CD30+ large cell lymphoma of natural killer cell phenotype bearing the t(2;5)(p23;q35) translocation and presenting in a child. Am J Dermatopathol 2000; 22(5): 422–8.
- Kadin ME. Characteristic immunologic profile of large atypical cells in lymphomatoid papulosis. Possible implications for histogenesis and relationship to other diseases. Arch Dermatol 1986; 122(12): 1388–90.
-
Nakamura S, Takagi N, Kojima M et al. Clinicopathologic study of large cell anaplastic lymphoma (Ki-1-positive large cell lymphoma) among the Japanese. Cancer 1991; 68(1): 118–29.
10.1002/1097-0142(19910701)68:1<118::AID-CNCR2820680123>3.0.CO;2-R CAS PubMed Web of Science® Google Scholar
- Kacerovska D, Michal M, Kazakov DV. Pediatric case of primary cutaneous eosinophil-rich CD30+ anaplastic large-cell lymphoma with follicular mucinosis. Am J Dermatopathol 2014; 36(3): e78–80.
- Kocabaş E, Türel Ermertcan A, Akinci S et al. Primary cutaneous CD30-positive anaplastic large cell lymphoma in a 16-year-old girl. Int J Dermatol 2012; 51(11): 1353–8.
- Santiago-et-Sánchez-Mateos D, Hernández-Martín A, Colmenero I et al. Primary cutaneous anaplastic large cell lymphoma of the nasal tip in a child. Pediatr Dermatol 2011; 28(5): 570–5.
- Vaid R, Cohen B. Primary cutaneous CD30 positive anaplastic large cell lymphoma in an adolescent. Pediatr Dermatol 2009; 26(6): 721–4.
- Yu JB, Blitzblau RC, Decker RH et al. Analysis of primary CD30+ cutaneous lymphoproliferative disease and survival from the Surveillance, Epidemiology, and End Results database. J Clin Oncol 2008; 26(9): 1483–8.
- Seo A, Lee S, Choi Y et al. Congenital primary cutaneous anaplastic large-cell lymphoma: a case report. Am J Dermatopathol 2015; 37(5): 398–400.
- Paulli M, Berti E, Rosso R et al. CD30/Ki-1-positive lymphoproliferative disorders of the skin – clinicopathologic correlation and statistical analysis of 86 cases: a multicentric study from the European Organization for Research and Treatment of Cancer Cutaneous Lymphoma Project Group. J Clin Oncol 1995; 13(6): 1343–54.
- Kaudewitz P, Stein H, Dallenbach F et al. Primary and secondary cutaneous Ki-1+ (CD30+) anaplastic large cell lymphomas. Morphologic, immunohistologic, and clinical-characteristics. Am J Pathol 1989; 135(2): 359–67.
- Kummer JA, Vermeer MH, Dukers D et al. Most primary cutaneous CD30-positive lymphoproliferative disorders have a CD4-positive cytotoxic T-cell phenotype. J Invest Dermatol 1997; 109(5): 636–40.
- Massone C, Cerroni L. Phenotypic variability in primary cutaneous anaplastic large T-cell lymphoma: a study on 35 patients. Am J Dermatopathol 2014; 36(2): 153–7.
- De Souza A, Tinguely M, Pfaltz M et al. Loss of expression of 5-hydroxymethylcytosine in CD30-positive cutaneous lymphoproliferative disorders. J Cutan Pathol 2014; 41(12): 901–6.
- Wood GS, Hardman DL, Boni R et al. Lack of the t(2;5) or other mutations resulting in expression of anaplastic lymphoma kinase catalytic domain in CD30+ primary cutaneous lymphoproliferative disorders and Hodgkin's disease. Blood 1996; 88(5): 1765–70.
- Oschlies I, Lisfeld J, Lamant L et al. ALK-positive anaplastic large cell lymphoma limited to the skin: clinical, histopathological and molecular analysis of 6 pediatric cases. A report from the ALCL99 study. Haematologica 2013; 98(1): 50–6.
- DeCoteau JF, Butmarc JR, Kinney MC, Kadin ME. The t(2;5) chromosomal translocation is not a common feature of primary cutaneous CD30+ lymphoproliferative disorders: comparison with anaplastic large-cell lymphoma of nodal origin. Blood 1996; 87(8): 3437–41.
- Kiran T, Demirkesen C, Eker C et al. The significance of MUM1/IRF4 protein expression and IRF4 translocation of CD30(+) cutaneous T-cell lymphoproliferative disorders: a study of 53 cases. Leuk Res 2013; 37(4): 396–400.
- Wada DA, Law ME, Hsi ED et al. Specificity of IRF4 translocations for primary cutaneous anaplastic large cell lymphoma: a multicenter study of 204 skin biopsies. Mod Pathol 2011; 24(4): 596–605.
- Liu HL, Hoppe RT, Kohler S et al. CD30+ cutaneous lymphoproliferative disorders: the Stanford experience in lymphomatoid papulosis and primary cutaneous anaplastic large cell lymphoma. J Am Acad Dermatol 2003; 49(6): 1049–58.
- Macaulay WL. Lymphomatoid papulosis. A continuing self-healing eruption, clinically benign – histologically malignant. Arch Dermatol 1968; 97(1): 23–30.
-
Wang HH, Lach L, Kadin ME. Epidemiology of lymphomatoid papulosis. Cancer 1992; 70(12): 2951–7.
10.1002/1097-0142(19921215)70:12<2951::AID-CNCR2820701236>3.0.CO;2-7 CAS PubMed Web of Science® Google Scholar
- Boccara O, Blanche S, de Prost Y et al. Cutaneous hematologic disorders in children. Pediatr Blood Cancer 2012; 58(2): 226–32.
- Nijsten T, Curiel-Lewandrowski C, Kadin ME. Lymphomatoid papulosis in children: a retrospective cohort study of 35 cases. Arch Dermatol 2004; 140(3): 306–12.
- Miquel J, Fraitag S, Hamel-Teillac D et al. Lymphomatoid papulosis in children: a series of 25 cases. Br J Dermatol 2014; 171(5): 1138–46.
- Thomsen K, Wantzin GL. Lymphomatoid papulosis. A follow-up study of 30 patients. J Am Acad Dermatol 1987; 17(4): 632–6.
- Thomas GJ, Conejo-Mir JS, Ruiz AP et al. Lymphomatoid papulosis in childhood with exclusive acral involvement. Pediatr Dermatol 1998; 15(2): 146–7.
- El-Shabrawi-Caelen L, Kerl H, Cerroni L. Lymphomatoid papulosis: reappraisal of clinicopathologic presentation and classification into subtypes A, B, and C. Arch Dermatol 2004; 140(4): 441–7.
- Scarisbrick JJ, Evans AV, Woolford AJ et al. Regional lymphomatoid papulosis: a report of four cases. Br J Dermatol 1999; 141(6): 1125–8.
- Kempf W. CD30+ lymphoproliferative disorders: histopathology, differential diagnosis, new variants, and simulators. J Cutan Pathol 2006; 33 Suppl 1(S1): 58–70.
- Saggini A, Gulia A, Argenyi Z et al. A variant of lymphomatoid papulosis simulating primary cutaneous aggressive epidermotropic CD8+ cytotoxic T-cell lymphoma. Description of 9 cases. Am J Surg Pathol 2010; 34(8): 1168–75.
- Plaza JA, Feldman AL, Magro C. Cutaneous CD30-positive lymphoproliferative disorders with CD8 expression: a clinicopathologic study of 21 cases. J Cutan Pathol 2013; 40(2): 236–47.
- McQuitty E, Curry JL, Tetzlaff MT et al. The differential diagnosis of CD8-positive (‘type D’) lymphomatoid papulosis. J Cutan Pathol 2014; 41(2): 88–100.
- Kempf W, Kazakov DV, Schärer L et al. Angioinvasive lymphomatoid papulosis: a new variant simulating aggressive lymphomas. Am J Surg Pathol 2013; 37(1): 1–13.
- Karai LJ, Kadin ME, Hsi ED et al. Chromosomal rearrangements of 6p25.3 define a new subtype of lymphomatoid papulosis. Am J Surg Pathol 2013; 37(8): 1173–81.
- Kadin ME. Common activated helper-T-cell origin for lymphomatoid papulosis, mycosis fungoides, and some types of Hodgkin's disease. Lancet 1985; 2(8460): 864–5.
- Kaudewitz P, Burg G, Stein H et al. Monoclonal antibody patterns in lymphomatoid papulosis. Dermatol Clin 1985; 3(4): 749–57.
- Varga FJ, Vonderheid EC, Olbricht SM, Kadin ME. Immunohistochemical distinction of lymphomatoid papulosis and pityriasis lichenoides et varioliformis acuta. Am J Pathol 1990; 136(4): 979–87.
- Harvell J, Vaseghi M, Natkunam Y et al. Large atypical cells of lymphomatoid papulosis are CD56-negative: a study of 18 cases. J Cutan Pathol 2002; 29(2): 88–92.
- Mateo S, Vázquez Osorio I, José Seoane M et al. Unusual CD8 positive lymphomatoid papulosis in childhood. Dermatol Online J 2014; 20(11).
- Kempf W, Kazakov DV, Baumgartner H-P, Kutzner H. Follicular lymphomatoid papulosis revisited: a study of 11 cases, with new histopathological findings. J Am Acad Dermatol 2013; 68(5): 809–16.
-
Wang HH, Myers T, Lach LJ et al. Increased risk of lymphoid and nonlymphoid malignancies in patients with lymphomatoid papulosis. Cancer 1999; 86(7): 1240–5.
10.1002/(SICI)1097-0142(19991001)86:7<1240::AID-CNCR19>3.0.CO;2-X CAS PubMed Web of Science® Google Scholar
- Kempf W, Levi E, Kamarashev J et al. Fascin expression in CD30-positive cutaneous lymphoproliferative disorders. J Cutan Pathol 2002; 29(5): 295–300.
- Kunishige JH, McDonald H, Alvarez G et al. Lymphomatoid papulosis and associated lymphomas: a retrospective case series of 84 patients. Clin Exp Dermatol 2009; 34(5): 576–81.
- Wantzin GL, Thomsen K. PUVA-treatment in lymphomatoid papulosis. Br J Dermatol 1982; 107(6): 687–90.
- Lynch PJ, Saied NK. Methotrexate treatment of pityriasis lichenoides and lymphomatoid papulosis. Cutis 1979; 23(5): 634–6.
- Johnston EE, LeBlanc RE, Kim J et al. Subcutaneous panniculitis-like T-cell lymphoma: pediatric case series demonstrating heterogeneous presentation and option for watchful waiting. Pediatr Blood Cancer 2015; 62(11): 2025–8.
- Chinello M, Naviglio S, Remotti D et al. Subcutaneous panniculitis-like T-cell lymphoma presenting with diffuse cutaneous edema in a 2-year-old child. J Pediatr Hematol Oncol 2015; 37(4): 329–30.
- Kawachi Y, Furuta J-I, Fujisawa Y et al. Indolent subcutaneous panniculitis-like T cell lymphoma in a 1-year-old child. Pediatr Dermatol 2012; 29(3): 374–7.
- Mehta N, Wayne AS, Kim YH et al. Bexarotene is active against subcutaneous panniculitis-like T-cell lymphoma in adult and pediatric populations. Clin Lymphoma Myeloma Leuk 2012; 12(1): 20–5.
- Koh MJ-A, Sadarangani SP, Chan Y-C et al. Aggressive subcutaneous panniculitis-like T-cell lymphoma with hemophagocytosis in two children (subcutaneous panniculitis-like T-cell lymphoma). J Am Acad Dermatol 2009; 61(5): 875–81.
- Lim G-Y, Hahn ST, Chung NG, Kim HK. Subcutaneous panniculitis-like T-cell lymphoma in a child: whole-body MRI in the initial and follow-up evaluations. Pediatr Radiol 2009; 39(1): 57–61.
- Jaffe ES, Ralfkier E. Subcutaneous panniculitis like T-cell lymphoma. In: ES Jaffe, NL Harris, H Stein (eds) World Health Organization Classification of Tumors: Tumors of Haemapoietic and Lymphoid Tissues. IARC: Lyon, 2001: 212–15.
- Oschlies I, Simonitsch-Klupp I, Maldyk J et al. Subcutaneous panniculitis-like T-cell lymphoma in children: a detailed clinicopathological description of 11 multifocal cases with a high frequency of haemophagocytic syndrome. Br J Dermatol 2015; 172(3): 793–7.
- Salhany KE, Macon WR, Choi JK et al. Subcutaneous panniculitis-like T-cell lymphoma: clinicopathologic, immunophenotypic, and genotypic analysis of alpha/beta and gamma/delta subtypes. Am J Surg Pathol 1998; 22(7): 881–93.
- Ikeda E, Endo M, Uchigasaki S et al. Phagocytized apoptotic cells in subcutaneous panniculitis-like T-cell lymphoma. J Eur Acad Dermatol Venereol 2001; 15(2): 159–62.
- Kumar S, Krenacs L, Medeiros J et al. Subcutaneous panniculitic T-cell lymphoma is a tumor of cytotoxic T lymphocytes. Hum Pathol 1998; 29(4): 397–403.
- Parveen Z, Thompson K. Subcutaneous panniculitis-like T-cell lymphoma: redefinition of diagnostic criteria in the recent World Health Organization-European Organization for Research and Treatment of Cancer classification for cutaneous lymphomas. Arch Pathol Lab Med 2009; 133(2): 303–8.
- Harada H, Iwatsuki K, Kaneko F. Detection of Epstein–Barr virus genes in malignant lymphoma with clinical and histologic features of cytophagic histiocytic panniculitis. J Am Acad Dermatol 1994; 31(2 Pt 2): 379–83.
- Go RS, Wester SM. Immunophenotypic and molecular features, clinical outcomes, treatments, and prognostic factors associated with subcutaneous panniculitis-like T-cell lymphoma: a systematic analysis of 156 patients reported in the literature. Cancer 2004; 101(6): 1404–13.
- Shani-Adir A, Lucky AW, Prendiville J et al. Subcutaneous panniculitic T-cell lymphoma in children: response to combination therapy with cyclosporine and chemotherapy. J Am Acad Dermatol 2004; 50(2 Suppl): S18–22.
- Mraz-Gernhard S, Natkunam Y, Hoppe RT et al. Natural killer/natural killer-like T-cell lymphoma, CD56+, presenting in the skin: an increasingly recognized entity with an aggressive course. J Clin Oncol 2001; 19(8): 2179–88.
- Gniadecki R, Rossen K, Ralfkier E et al. CD56+ lymphoma with skin involvement: clinicopathologic features and classification. Arch Dermatol 2004; 140(4): 427–36.
- Ko YH, Cho E-Y, Kim J-E et al. NK and NK-like T-cell lymphoma in extranasal sites: a comparative clinicopathological study according to site and EBV status. Histopathology 2004; 44(5): 480–9.
- Pol-Rodriguez MM, Fox LP, Sulis ML et al. Extranodal nasal-type natural killer T-cell lymphoma in an adolescent from Bangladesh. J Am Acad Dermatol 2006; 54(5 Suppl): S192–7.
-
Shaw PH, Cohn SL, Morgan ER et al. Natural killer cell lymphoma: report of two pediatric cases, therapeutic options, and review of the literature. Cancer 2001; 91(4): 642–6.
10.1002/1097-0142(20010215)91:4<642::AID-CNCR1047>3.0.CO;2-2 CAS PubMed Web of Science® Google Scholar
- Wang P, Sun Y, Wang Z, Xu A. Primary cutaneous extranodal NK/T-cell lymphoma, nasal type, in an adolescent. Eur J Dermatol 2010; 20(1): 130–1.
- Rodríguez-Pinilla SM, Barrionuevo C, Garcia J et al. EBV-associated cutaneous NK/T-cell lymphoma: review of a series of 14 cases from peru in children and young adults. Am J Surg Pathol 2010; 34(12): 1773–82.
- Sandner A, Helmbold P, Winkler M et al. Cutaneous dissemination of nasal NK/T-cell lymphoma in a young girl. Clin Exp Dermatol 2008; 33(5): 615–18.
- Yu J-B, Zuo Z, Tang Y et al. Extranodal nasal-type natural killer/T-cell lymphoma of the skin: a clinicopathologic study of 16 cases in China. Hum Pathol 2009; 40(6): 807–16.
- Barrionuevo C, Anderson VM, Zevallos-Giampietri E et al. Hydroa-like cutaneous T-cell lymphoma: a clinicopathologic and molecular genetic study of 16 pediatric cases from Peru. Appl Immunohistochem Mol Morphol 2002; 10(1): 7–14.
- Chen H, Hsiao C, Chiu H. Hydroa vacciniforme-like primary cutaneous CD8-positive T-cell lymphoma. Br J Dermatol 2002; 147(3): 587–91.
- Iwatsuki K, Satoh M, Yamamoto T et al. Pathogenic link between hydroa vacciniforme and Epstein–Barr virus-associated hematologic disorders. Arch Dermatol 2006; 142(5): 587–95.
- Magaña M, Sangüeza P, Gil-Beristain J et al. Angiocentric cutaneous T-cell lymphoma of childhood (hydroa-like lymphoma): a distinctive type of cutaneous T-cell lymphoma. J Am Acad Dermatol 1998; 38(4): 574–9.
- Quintanilla-Martinez L, Ridaura C, Nagl F et al. Hydroa vacciniforme-like lymphoma: a chronic EBV+ lymphoproliferative disorder with risk to develop a systemic lymphoma. Blood 2013; 122(18): 3101–10.
- Cho KH, Kim C-W, Lee D-Y et al. An Epstein–Barr virus-associated lymphoproliferative lesion of the skin presenting as recurrent necrotic papulovesicles of the face. Br J Dermatol 1996; 134(4): 791–6.
- Sangueza M, Plaza JA. Hydroa vacciniforme-like cutaneous T-cell lymphoma: clinicopathologic and immunohistochemical study of 12 cases. J Am Acad Dermatol 2013; 69(1): 112–19.
- Plaza JA, Sangueza M. Hydroa vacciniforme-like lymphoma with primarily periorbital swelling: 7 cases of an atypical clinical manifestation of this rare cutaneous T-cell lymphoma. Am J Dermatopathol 2015; 37(1): 20–5.
- Xu Z, Lian S. Epstein–Barr virus-associated hydroa vacciniforme-like cutaneous lymphoma in seven Chinese children. Pediatr Dermatol 2010; 27(5): 463–9.
- Wu Y-H, Chen H-C, Hsiao P-F et al. Hydroa vacciniforme-like Epstein–Barr virus-associated monoclonal T-lymphoproliferative disorder in a child. Int J Dermatol 2007; 46(10): 1081–6.
- Li Y, Chen X-H, Tian X-Y et al. Primary cutaneous hydroa vacciniforme-like lymphoma with indolent clinical course: report of two cases and review of literature. Int J Surg Pathol 2013; 21(2): 161–8.
- Beltrán BE, Maza I, Moisés-Alfaro CB et al. Thalidomide for the treatment of hydroa vacciniforme-like lymphoma: report of four pediatric cases from Peru. Am J Hematol 2014; 89(12): 1160–1.
- Taddesse-Heath L, Pittaluga S, Sorbara L et al. Marginal zone B-cell lymphoma in children and young adults. Am J Surg Pathol 2003; 27(4): 522–31.
- Kempf W, Kazakov DV, Buechner SA et al. Primary cutaneous marginal zone lymphoma in children: a report of 3 cases and review of the literature. Am J Dermatopathol 2014; 36(8): 661–6.
- Ghatalia P, Porter J, Wroblewski D, Carlson JA. Primary cutaneous marginal zone lymphoma associated with juxta-articular fibrotic nodules in a teenager. J Cutan Pathol 2013; 40(5): 477–84.
- Park MY, Jung HJ, Park JE, Kim YC. Pediatric primary cutaneous marginal zone B-cell lymphoma treated with intralesional rituximab. Eur J Dermatol 2010; 20(4): 533–4.
- Amitay-Laish I, Feinmesser M, Ben-Amitai D et al. Juvenile onset of primary low-grade cutaneous B-cell lymphoma. Br J Dermatol 2009; 161(1): 140–7.
- Sharon V, Mecca PS, Steinherz PG et al. Two pediatric cases of primary cutaneous B-cell lymphoma and review of the literature. Pediatr Dermatol 2009; 26(1): 34–9.
- Cerroni L, Zöchling N, Pütz B, Kerl H. Infection by Borrelia burgdorferi and cutaneous B-cell lymphoma. J Cutan Pathol 1997; 24(8): 457–61.
- Goodlad J, Davidson M, Hollowood K et al. Borrelia burgdorferi-associated cutaneous marginal zone lymphoma: a clinicopathological study of two cases illustrating the temporal progression of B. burgdorferi-associated B-cell proliferation in the skin. Histopathology 2000; 37(6): 501–8.
- Li C, Inagaki H, Kuo T-T et al. Primary cutaneous marginal zone B-cell lymphoma: a molecular and clinicopathologic study of 24 asian cases. Am J Surg Pathol 2003; 27(8): 1061–9.
- Wood GS, Kamath NV, Guitart J et al. Absence of Borrelia burgdorferi DNA in cutaneous B-cell lymphomas from the United States. J Cutan Pathol 2001; 28(10): 502–7.
- Suarez F, Lortholary O, Hermine O, Lecuit M. Infection-associated lymphomas derived from marginal zone B cells: a model of antigen-driven lymphoproliferation. Blood 2006; 107(8): 3034–44.
- Sroa N, Magro CM. Pediatric primary cutaneous marginal zone lymphoma: in association with chronic antihistamine use. J Cutan Pathol 2006; 33 Suppl 2(s2): 1–5.
- Guitart J, Deonizio J, Bloom T et al. High incidence of gastrointestinal tract disorders and autoimmunity in primary cutaneous marginal zone B-cell lymphomas. JAMA Dermatol 2014; 150(4): 412–18.
- Baldassano MF, Bailey EM, Ferry JA et al. Cutaneous lymphoid hyperplasia and cutaneous marginal zone lymphoma: comparison of morphologic and immunophenotypic features. Am J Surg Pathol 1999; 23(1): 88–96.
- Cerroni L, Signoretti S, Höfler G et al. Primary cutaneous marginal zone B-cell lymphoma: a recently described entity of low-grade malignant cutaneous B-cell lymphoma. Am J Surg Pathol 1997; 21(11): 1307–15.
- Brenner I, Roth S, Puppe B et al. Primary cutaneous marginal zone lymphomas with plasmacytic differentiation show frequent IgG4 expression. Mod Pathol 2013; 26(12): 1568–76.
- de Leval L, Harris NL, Longtine J et al. Cutaneous b-cell lymphomas of follicular and marginal zone types: use of Bcl-6, CD10, Bcl-2, and CD21 in differential diagnosis and classification. Am J Surg Pathol 2001; 25(6): 732–41.
- Goyal A, Moore JB, Gimbel D et al. PD-1, S-100 and CD1a expression in pseudolymphomatous folliculitis, primary cutaneous marginal zone B-cell lymphoma (MALT lymphoma) and cutaneous lymphoid hyperplasia. J Cutan Pathol 2015; 42(1): 6–15.
- Golling P, Cozzio A, Dummer R et al. Primary cutaneous B-cell lymphomas – clinicopathological, prognostic and therapeutic characterisation of 54 cases according to the WHO-EORTC classification and the ISCL/EORTC TNM classification system for primary cutaneous lymphomas other than mycosis fungoides and Sezary syndrome. Leuk Lymphoma 2008; 49(6): 1094–103.
- Gerami P, Wickless SC, Querfeld C et al. Cutaneous involvement with marginal zone lymphoma. J Am Acad Dermatol 2010; 63(1): 142–5.
- Soda R, Costanzo A, Cantonetti M et al. Systemic therapy of primary cutaneous B-cell lymphoma, marginal zone type, with rituximab, a chimeric anti-CD20 monoclonal antibody. Acta Derm Venereol 2001; 81(3): 207–8.
- Wollina U, Hahnfeld S, Kosmehl H. Primary cutaneous marginal center lymphoma – complete remission induced by interferon alpha2a. J Cancer Res Clin Oncol 1999; 125(5): 305–8.
- Ghislanzoni M, Gambini D, Perrone T et al. Primary cutaneous follicular center cell lymphoma of the nose with maxillary sinus involvement in a pediatric patient. J Am Acad Dermatol 2005; 52(5 Suppl 1): S73–5.
- Condarco T, Sagatys E, Prakash AV et al. Primary cutaneous B-cell lymphoma in a child. Fetal Pediatr Pathol 2008; 27(4-5): 206–14.
- Cerroni L, Arzberger E, Pütz B et al. Primary cutaneous follicle center cell lymphoma with follicular growth pattern. Blood 2000; 95(12): 3922–8.
- Hoefnagel JJ, Vermeer MH, Jansen PM et al. Bcl-2, Bcl-6 and CD10 expression in cutaneous B-cell lymphoma: further support for a follicle centre cell origin and differential diagnostic significance. Br J Dermatol 2003; 149(6): 1183–91.
- Cerroni L, Volkenandt M, Rieger E et al. bcl-2 protein expression and correlation with the interchromosomal 14;18 translocation in cutaneous lymphomas and pseudolymphomas. J Invest Dermatol 1994; 102(2): 231–5.
- Bergman R, Kurtin PJ, Gibson LE et al. Clinicopathologic, immunophenotypic, and molecular characterization of primary cutaneous follicular B-cell lymphoma. Arch Dermatol 2001; 137(4): 432–9.
- Streubel B, Scheucher B, Valencak J et al. Molecular cytogenetic evidence of t(14;18)(IGH;BCL2) in a substantial proportion of primary cutaneous follicle center lymphomas. Am J Surg Pathol 2006; 30(4): 529–36.
- Aguilera NS, Tomaszewski MM, Moad JC et al. Cutaneous follicle center lymphoma: a clinicopathologic study of 19 cases. Mod Pathol 2001; 14(9): 828–35.
- Willemze R, Kerl H, Sterry W et al. EORTC classification for primary cutaneous lymphomas: a proposal from the Cutaneous Lymphoma Study Group of the European Organization for Research and Treatment of Cancer. Blood 1997; 90(1): 354–71.
- Vermeer MH, Geelen FA, van Haselen CW et al. Primary cutaneous large B-cell lymphomas of the legs. A distinct type of cutaneous B-cell lymphoma with an intermediate prognosis. Dutch Cutaneous Lymphoma Working Group. Arch Dermatol 1996; 132(11): 1304–8.
- Hallermann C, Niermann C, Fischer R-J, Schulze H-J. New prognostic relevant factors in primary cutaneous diffuse large B-cell lymphomas. J Am Acad Dermatol 2007; 56(4): 588–97.
- Kodama K, Fink-Puches R, Massone C et al. Papular mycosis fungoides: a new clinical variant of early mycosis fungoides. J Am Acad Dermatol 2005; 52(4): 694–8.
- Kodama K, Massone C, Chott A et al. Primary cutaneous large B-cell lymphomas: clinicopathologic features, classification, and prognostic factors in a large series of patients. Blood 2005; 106(7): 2491–7.
- Goodlad JR, Krajewski AS, Batstone PJ et al. Primary cutaneous diffuse large B-cell lymphoma: prognostic significance of clinicopathological subtypes. Am J Surg Pathol 2003; 27(12): 1538–45.
- Ponzoni M, Ferreri AJM, Campo E et al. Definition, diagnosis, and management of intravascular large B-cell lymphoma: proposals and perspectives from an international consensus meeting. J Clin Oncol 2007; 25: 3168–73.
- Reyes-Castro M, Vega-Memije E. Intravascular large cell lymphoma. Int J Dermatol 2007; 46(6): 619–21.
- Chan J, Jaffe ES, Ralfkiaer E. Blastic NK lymphoma. In: ES Jaffe, NL Harris, H Stein (eds) Pathology and Genetics of Tumours of Haemapoietic and Lymphoid Tissues. IARC: Lyon, 2001: 214–15.
- Grouard G, Rissoan MC, Filgueira L et al. The enigmatic plasmacytoid T cells develop into dendritic cells with interleukin (IL)-3 and CD40-ligand. J Exp Med 1997; 185(6): 1101–11.
- Herling M, Jones D. CD4+/CD56+ hematodermic tumor: the features of an evolving entity and its relationship to dendritic cells. Am J Clin Pathol 2007; 127(5): 687–700.
- Petrella T, Comeau MR, Maynadié M et al. Agranular CD4+ CD56+ hematodermic neoplasm’ (blastic NK-cell lymphoma) originates from a population of CD56+ precursor cells related to plasmacytoid monocytes. Am J Surg Pathol 2002; 26(7): 852–62.
- Chang SE, Choi HJ, Huh J et al. A case of primary cutaneous CD56+, TdT+, CD4+, blastic NK-cell lymphoma in a 19-year-old woman. Am J Dermatopathol 2002; 24(1): 72–5.
- Ruggiero A, Maurizi P, Larocca LM et al. Childhood CD4+/CD56+ hematodermic neoplasm: case report and review of the literature. Haematologica 2006; 91(12 Suppl): ECR48.
- Chan JK, Sin VC, Wong KF et al. Nonnasal lymphoma expressing the natural killer cell marker CD56: a clinicopathologic study of 49 cases of an uncommon aggressive neoplasm. Blood 1997; 89(12): 4501–13.
- Zhong X-D, Wang L-Z, Wang X, Chang J. Diffuse lung metastases in a child with blastic plasmacytoid dendritic cell neoplasm and review. Eur J Pediatr 2014; 173(12): 1667–70.
- Yang C, Wang J, Chang T. Congenital blastic plasmacytoid dendritic cell neoplasm. Pediatr Blood Cancer 2012; 58(1): 109–10.
- Julia F, Petrella T, Beylot-Barry M et al. Blastic plasmacytoid dendritic cell neoplasm: clinical features in 90 patients. Br J Dermatol 2013; 169(3): 579–86.
- DiGiuseppe JA, Louie DC, Williams JE et al. Blastic natural killer cell leukemia/lymphoma: a clinicopathologic study. Am J Surg Pathol 1997; 21(10): 1223–30.
- Petrella T, Dalac S, Maynadié M et al. CD4+ CD56+ cutaneous neoplasms: a distinct hematological entity? Groupe Français d'Etude des Lymphomes Cutanés (GFELC). Am J Surg Pathol 1999; 23(2): 137–46.
- Chaperot L, Bendriss N, Manches O et al. Identification of a leukemic counterpart of the plasmacytoid dendritic cells. Blood 2001; 97(10): 3210–17.
- Herling M, Teitell MA, Shen RR et al. TCL1 expression in plasmacytoid dendritic cells (DC2s) and the related CD4+ CD56+ blastic tumors of skin. Blood 2003; 101(12): 5007–9.
-
Brody JP, Allen S, Schulman P et al. Acute agranular CD4-positive natural killer cell leukemia. Comprehensive clinicopathologic studies including virologic and in vitro culture with inducing agents. Cancer 1995; 75(10): 2474–83.
10.1002/1097-0142(19950515)75:10<2474::AID-CNCR2820751013>3.0.CO;2-Y CAS PubMed Web of Science® Google Scholar
- Hallermann C, Middel P, Griesinger F et al. CD4+ CD56+ blastic tumor of the skin: cytogenetic observations and further evidence of an origin from plasmocytoid dendritic cells. Eur J Dermatol 2004; 14(5): 317–22.
- Feuillard J, Jacob M-C, Valensi F et al. Clinical and biologic features of CD4(+)CD56(+) malignancies. Blood 2002; 99(5): 1556–63.
- Rossi JG, Felice MS, Bernasconi AR et al. Acute leukemia of dendritic cell lineage in childhood: incidence, biological characteristics and outcome. Leuk Lymphoma 2006; 47(4): 715–25.
- Hashikawa K, Niino D, Yasumoto S et al. Clinicopathological features and prognostic significance of CXCL12 in blastic plasmacytoid dendritic cell neoplasm. J Am Acad Dermatol 2012; 66(2): 278–91.