Depression
Camilla S. Hanson
Sydney School of Public Health University of Sydney, Sydney, NSW, Australia
Centre for Kidney Research, The Children's Hospital at Westmead, Westmead, NSW, Australia
Search for more papers by this authorCharlotte Logeman
Sydney School of Public Health University of Sydney, Sydney, NSW, Australia
Centre for Kidney Research, The Children's Hospital at Westmead, Westmead, NSW, Australia
Search for more papers by this authorMary Amanda Dew
Department of Psychiatry, University of Pittsburgh School of Medicine and Medical Center, Pittsburgh, PA, USA
Search for more papers by this authorSuetonia C. Palmer
Department of Medicine, University of Otago Christchurch, Christchurch, Canterbury, New Zealand
Search for more papers by this authorCamilla S. Hanson
Sydney School of Public Health University of Sydney, Sydney, NSW, Australia
Centre for Kidney Research, The Children's Hospital at Westmead, Westmead, NSW, Australia
Search for more papers by this authorCharlotte Logeman
Sydney School of Public Health University of Sydney, Sydney, NSW, Australia
Centre for Kidney Research, The Children's Hospital at Westmead, Westmead, NSW, Australia
Search for more papers by this authorMary Amanda Dew
Department of Psychiatry, University of Pittsburgh School of Medicine and Medical Center, Pittsburgh, PA, USA
Search for more papers by this authorSuetonia C. Palmer
Department of Medicine, University of Otago Christchurch, Christchurch, Canterbury, New Zealand
Search for more papers by this authorJonathan C. Craig MBChB, DipCH, MMed(Clin Epi), PhD, FAHMS
Matthew Flinders Distinguished Professor Vice President and Executive Dean
College of Medicine and Public Health, Flinders University, Adelaide, Australia
Search for more papers by this authorDonald A. Molony MD
Professor of Medicine Distinguished Teaching Professor of the University of Texas System
Division of Renal Diseases and Hypertension AND Center for Clinical Research and Evidence-based Medicine, McGovern Medical School University of Texas, Houston, TX, USA
Search for more papers by this authorGiovanni F.M. Strippoli MD, PhD, MPH, MM (Epi)
Professor of Nephrology Adjunct Professor of Epidemiology
Department of Emergency and Organ Transplantation – University of Bari, Bari, Italy
School of Public Health, University of Sydney, Sydney, NSW, Australia
Search for more papers by this authorSummary
Major depressive disorder (MDD) is common among patients with chronic kidney disease (CKD) and end-stage kidney disease, more so than in other chronic conditions, and is associated with a range of adverse clinical outcomes. It is not known whether depression in patients with CKD is different from depression that is seen in individuals without a comorbid chronic medical condition, and in particular whether depressive symptom severity and the efficacy of treatment is modified by decrements in kidney function. Studies of patients with CKD and end-stage kidney disease have identified vastly different estimates of the prevalence of depression. Compared to studies assessing depression among hemodialysis populations, there are limited studies among individuals receiving peritoneal dialysis and the available studies involve relatively small samples of patients. The studies assessing the prevalence of depression among kidney transplant populations are predominately small single-center samples.
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