Chapter 46

Salt and Water Balance

Mathew Tabinor

Mathew Tabinor

Renal Research Group, Faculty of Medicine and Applied Clinical Sciences, Keele University, Newcastle-under-Lyme, UK

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Mark Lambie

Mark Lambie

Renal Research Group, Faculty of Medicine and Applied Clinical Sciences, Keele University, Newcastle-under-Lyme, UK

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Simon J. Davies

Simon J. Davies

Renal Research Group, Faculty of Medicine and Applied Clinical Sciences, Keele University, Newcastle-under-Lyme, UK

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First published: 18 November 2022

Summary

Achieving salt and water balance is fundamental to optimizing fluid status, one of the key objectives of peritoneal dialysis (PD) treatment. The relative importance of salt and water management to patient outcomes was historically underestimated by early treatment guidelines, which tended to focus on small solute clearance as the principal metric of dialysis adequacy. Hypertension is common in PD patients and, given the high cardiovascular morbidity and mortality in dialysis patients, it is a crucial aspect of patient management. Bioimpedance is increasingly used to assess body composition in dialysis patients. Given the predictive value of bioimpedance, it is natural to ask if it can be used to guide and thus improve fluid management in dialysis patients. The problems of poor salt and water balance in the context of fast small solute transfer are twofold: early loss of ultrafiltration in the dwell followed by more rapid reabsorption of salt and water.

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