This chapter highlights key topics that contribute to the progress toward more sustainable packaging for food and beverages and points to the opportunity for packaging to have an added function as a valuable resource that can feed into the production of new products. It reviews the packaging materials and considerations based on their origin of renewable, nonrenewable, or recycled materials. The environmental and social hotspots with packaging can be addressed to help it be effective, efficient, cyclic, and safe—responsible packaging (or more sustainable packaging) is often defined to include the following: (1) being beneficial, safe, and healthy for individuals and communities throughout its life cycle, (2) manufactured using clean production technologies and best practices and (3) physically designed to optimize materials and energy. The traditional waste hierarchy of reduce-reuse-recycle comes into play with designing to address end-of-life opportunities.