Chapter 9
Routes in Innate Immunity Evolution: Galectins and Rhamnose-binding Lectins in Ascidians
Loriano Ballarin,
Matteo Cammarata,
Nicola Franchi,
Nicolò Parrinello,
Loriano Ballarin
Department of Biology, University of Padova, Padova, Italy
Search for more papers by this authorMatteo Cammarata
Department of Environmental Biology and Biodiversity, University of Palermo, Palermo, Italy
Search for more papers by this authorNicola Franchi
Department of Biology, University of Padova, Padova, Italy
Search for more papers by this authorNicolò Parrinello
Department of Environmental Biology and Biodiversity, University of Palermo, Palermo, Italy
Search for more papers by this authorLoriano Ballarin,
Matteo Cammarata,
Nicola Franchi,
Nicolò Parrinello,
Loriano Ballarin
Department of Biology, University of Padova, Padova, Italy
Search for more papers by this authorMatteo Cammarata
Department of Environmental Biology and Biodiversity, University of Palermo, Palermo, Italy
Search for more papers by this authorNicola Franchi
Department of Biology, University of Padova, Padova, Italy
Search for more papers by this authorNicolò Parrinello
Department of Environmental Biology and Biodiversity, University of Palermo, Palermo, Italy
Search for more papers by this authorBook Editor(s):Se-Kwon Kim,
Se-Kwon Kim
Marine Bioprocess Research Center, Pukyong National University, Busan, Republic of Korea
Department of Chemistry, Pukyoung National University, Nam-Gu, Busan, Republic of Korea
Search for more papers by this authorSummary
Animal lectins are grouped in various molecular families, differing in carbohydrate-recognition domain (CRD) structure and organization. They are involved in a variety of key biological processes, ranging from development to immune responses. Ascidian lectins include galectins and rhamnose-binding proteins. The solitary ascidian species Ciona intestinalis and the colonial species Botryllus schlosseri are important model organisms for developmental and evolutionary biology studies, including immunobiology. This chapter talks about molecular features, structure and evolution of C. intestinalis galectins and involvement of galectins in C.intestinalis inflammatory response. It also talks about biochemical and molecular features, and synthesis and immune roles of Botryllus schlosseri rhamnose-binding lectins (RBLs).
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