Chapter 3

Olmesartan Medoxomil: An Angiotensin II Receptor Blocker

Hiroaki Yanagisawa

Hiroaki Yanagisawa

R&D Division, DAIICHI SANKYO Co., Ltd., Shinagawa-ku, Tokyo, Japan

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Hiroyuki Koike

Hiroyuki Koike

R&D Division, DAIICHI SANKYO Co., Ltd., Shinagawa-ku, Tokyo, Japan

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Shin-Ichiro Miura

Shin-Ichiro Miura

Department of Cardiology, Fukuoka University School of Medicine, Fukuoka, Japan

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First published: 11 May 2012
Citations: 1

Summary

This chapter contains sections titled:

  • Background

  • The Discovery of Olmesartan Medoxomil (Benicar)

  • Characteristics of Olmesartan

  • Binding Sites of Omlersartan to the AT1 Receptor and Its Inverse Agonoist Activity

  • Practical Preparation of Olmesartan Medoxomil

  • Preclinical Studies

  • Clinical Studies

  • Conclusion

  • References

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