Electrical Activity in Cardiac Tissue, Modeling of

S.L. Cloherty

S.L. Cloherty

University of New South Wales, Graduate School of Biomedical Engineering, Sydney, Australia

University of Newcastle, School of Engineering, Callaghan, Australia

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S. Dokos

S. Dokos

University of New South Wales, Graduate School of Biomedical Engineering, Sydney, Australia

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N.H. Lovell

N.H. Lovell

University of New South Wales, Graduate School of Biomedical Engineering, Sydney, Australia

Australian Technology Park, National ICT Australia (NICTA), Eveleigh, Australia

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First published: 14 April 2006
Citations: 1

Abstract

The heart is a complex organ, exhibiting significant variation in both structural and functional characteristics from one region to another. Mathematical modeling represents a powerful tool for improving our understanding of the mechanisms underlying both normal and abnormal cardiac function. This article describes the techniques routinely employed in modeling the electrical activity of the heart at the cellular and tissue scales. These techniques have proven useful in modeling the structural and functional characteristics in all areas of the heart and provide a foundation for constructing integrated models of the entire heart.

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