Hippocampus

Hamid Soltanian-Zadeh

Hamid Soltanian-Zadeh

Henry Ford Hospital, Detroit, Michigan

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Kost Elisevich

Kost Elisevich

Henry Ford Hospital, Detroit, Michigan

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First published: 14 April 2006

Abstract

The hippocampus (HC), a discrete anatomical landmark of the mesial temporal lobe of the brain, is part of the limbic system of the brain and subserves both learning and memory. Several clinical pathological entities are affected by the HC so that its clinical investigation has been a focus of intense work. Its intrinsic connectivity with its feedforward and feedback circuitry underlies a complex organization that, when disturbed, can give rise to debilitating conditions such as epilepsy. The application of electroencephalographic and imaging methodologies to the study of this structure has provided a means of not only lateralizing the site of pathology but determining the nature of the condition.

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