Pharmacotherapy for Traumatic Brain Injury

Neurodegenerative and Seizure Disorders
Donald G. Stein

Donald G. Stein

Emory University, Atlanta, Georgia

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Stuart W. Hoffman

Stuart W. Hoffman

Emory University, Atlanta, Georgia

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First published: 02 March 2007

Abstract

Currently there are no clinically approved, safe and effective treatments for traumatic brain injury (TBI) that can rescue damaged nerve cells and enhance functional recovery. This chapter shows that TBI is a complex cascade of events that unfolds over time and no single pharmacological agent has been found to block all the processes that comprise the injury. Here we review the categories of candidate agents and approaches that have been examined for their potential benefits in the treatment of TBI.

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