Chapter 18

Risk of Transmission of Prions with Medical Devices

S. Lori Brown PhD, MPH

S. Lori Brown PhD, MPH

Epidemiologist

Investigations Branch, Seattle District Office, Food and Drug Administration, 22201 23 rd Drive SE, Bothell, WA 98021, USA

Epidemiology Branch, Division of Postmarket Surveillance, Office of Surveillance and Biometrics, Center for Devices and Radiological Health, Food and Drug Administration, 1350 Piccard Drive, HFZ-541, Rockville, MD 20850, USA

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Azadeh Shoaibi MS, MHS

Azadeh Shoaibi MS, MHS

Epidemiologist

Epidemiology Branch, Division of Postmarket Surveillance, Office of Surveillance and Biometrics, Center for Devices and Radiological Health, Food and Drug Administration, 1350 Piccard Drive, HFZ-541, Rockville, MD 20850, USA

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First published: 02 March 2007

Summary

This chapter contains sections titled:

  • Iatrogenic transmission of prion disease via neurological or surgical instruments

  • Surgical instruments used to transplant tissues known to have transmitted prion disease (corneal transplant)

  • Surgical instruments in contact with lower risk peripheral tissues

  • Decontaminating surgical instruments to reduce risk of TSE transmission

  • FDA measures to minimize risk of transmission of BSE by medical products

  • Summary

  • References

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