Antibiotics, Production

Heinz Öppinger

Heinz Öppinger

Hoechst Aktiengesellschaft, Frankfurt, Germany

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Hinrich Hoffmann

Hinrich Hoffmann

Hoechst Aktiengesellschaft, Frankfurt, Germany

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Dieter Sukatsch

Dieter Sukatsch

Hoechst Aktiengesellschaft, Frankfurt, Germany

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Updated by Staff
First published: 25 July 2016

Abstract

The article contains sections titled:

1. Fermentation
1.1. Screening
1.2. Selection, Mutation, and Maintenance of Strains
1.3. Process Development Leading to Large-Scale Production
1.4. Fermentation Technology
1.4.1. Maintenance of the Strain and Production of Inoculum
1.4.2. Treatment Before and During Fermentation
2. Isolation and Purification of Antibiotics; Quality Specifications
2.1. Isolation
2.2. Purification Techniques, Sterile End Products, Official Regulations
3. Analytical Measurements and Quality Control
3.1. Microbiological Analysis
3.2. Isotopically Labeled Antibiotics

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