The Human Genome Project has changed biological science. Large volumes of raw data, including the sequence of the human genome, are readily accessible in public databases. The successes of the Human Genome Project have encouraged discussion of other industrial-scale data generation projects. Building from the warehouses of information, including catalogs of genes and genetic variants, gene expression profiles, protein-protein interactions and protein structures, it is expected that a focus on pharmacogenomics will facilitate rapid progress in drug development and treatment protocol design and result in significant improvements in healthcare.