[139354-61-3] C₃₉H₃₈O₄Ti (MW 618.23)

InChI = 1S/C31H28O4.C5H5.C3H5.Ti/c1-29(2)34-27(30(32,23-15-7-3-8-16-23)24-17-9-4-10-18-24)28(35-29)31(33,25-19-11-5-12-20-25)26-21-13-6-14-22-26;1-2-4-5-3-1;1-3-2;/h3-22,27-28H,1-2H3;1-5H;3H,1-2H2;/q-2;;;+2/t27-,28-;;;/m0.../s1

InChIKey = QKHHREYDRUIQSO-HVVJQNAGSA-N

[139354-59-4] C₃₉H₃₈O₄Ti (MW 618.23)

InChI = 1S/C31H28O4.C5H5.C3H5.Ti/c1-29(2)34-27(30(32,23-15-7-3-8-16-23)24-17-9-4-10-18-24)28(35-29)31(33,25-19-11-5-12-20-25)26-21-13-6-14-22-26;1-2-4-5-3-1;1-3-2;/h3-22,27-28H,1-2H3;1-5H;3H,1-2H2;/q-2;;;+2/t27-,28-;;;/m1.../s1

InChIKey = QKHHREYDRUIQSO-CRMRIEQBSA-N

(reagent for the asymmetric allyltitanation of aldehydes to produce homoallylic alcohols)²

Solubility: used as the crude preparation in Et₂O.

Analysis of Reagent Purity: ¹H NMR and ¹³C NMR (CD₂Cl₂).²

Preparative Methods: it can be prepared in two steps from either (4R,trans)-2,2-dimethyl-α,α,α′,α′-tetraphenyl-1,3-dioxolane-4,5-dimethanol (R,R-Taddol)³ or (4S,trans)-2,2-dimethyl-α,α,α′,α′-tetraphenyl-1,3-dioxolane-4,5-dimethanol (S,S-Taddol)³ (eq 1).²

Handling, Storage, and Precautions: best handled as stock solution in Et₂O (ca. 0.82 M) which must be protected from moisture. Should be used just after preparation. Reactions should be carried out in dry equipment and with absolute solvents under Ar or N₂.