Volume 14, Issue 2 pp. 120-121
Short Communication

Effect of Ocimum sanctum roots extract on swimming performance in mice

Tapan K. Maity

Tapan K. Maity

College of Pharmaceutical Sciences, Mohuda, Berhampur, Ganjam, Orissa - 760 002, India

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Subhash C. Mandal

Subhash C. Mandal

Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, Calcutta - 700 032, India

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B. P. Saha

B. P. Saha

Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, Calcutta - 700 032, India

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M. Pal

Corresponding Author

M. Pal

Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, Calcutta - 700 032, India

Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, Calcutta 700 032, IndiaSearch for more papers by this author

Abstract

The effect of a methanol extract, obtained from the roots of Ocimum sanctum, on mouse swimming performance were studied using three different doses. On the basis of our findings, a high dose (400 mg/kg, i.p.) of the extracts of Ocimum sanctum increased the swimming time suggesting a central nervous system stimulant and/or antistress activity. The effect produced by the extract was comparable to that of desipramine, an antidepressant drug. Copyright © 2000 John Wiley & Sons, Ltd.

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