Volume 12, Issue 8 pp. 592-594

Short Communication

Toxicological studies on Globularia alypum and Zygophyllum gaetulum in rats

F. Skim,

F. Skim

Laboratory of Waters and Environment, Department of Biology, Faculty of Sciences, 28/S, Agadir, Morocco

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B. H. Lazrek,

Corresponding Author

B. H. Lazrek

Laboratory of Phytochemistry, Department of Chemistry, Faculty of Sciences-Semlalia, P.O.B: S15, Marrakesh, Morocco

Laboratory of Phytochemistry, Department of Chemistry, Faculty of Sciences-Semlalia, POB S15, Marrakesh, MoroccoSearch for more papers by this author

H. El Amri,

H. El Amri

Laboratory of Toxico-Pharmacology, Fraternelle de la Gendarmerie Royale, Agdal, Rabat, Morocco

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A. Kaaya,

A. Kaaya

Laboratory of Waters and Environment, Department of Biology, Faculty of Sciences, 28/S, Agadir, Morocco

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M. Jana,

M. Jana

Laboratory of Phytochemistry, Department of Chemistry, Faculty of Sciences-Semlalia, P.O.B: S15, Marrakesh, Morocco

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F. Skim,

F. Skim

Laboratory of Waters and Environment, Department of Biology, Faculty of Sciences, 28/S, Agadir, Morocco

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B. H. Lazrek,

Corresponding Author

B. H. Lazrek

Laboratory of Phytochemistry, Department of Chemistry, Faculty of Sciences-Semlalia, P.O.B: S15, Marrakesh, Morocco

Laboratory of Phytochemistry, Department of Chemistry, Faculty of Sciences-Semlalia, POB S15, Marrakesh, MoroccoSearch for more papers by this author

H. El Amri,

H. El Amri

Laboratory of Toxico-Pharmacology, Fraternelle de la Gendarmerie Royale, Agdal, Rabat, Morocco

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A. Kaaya,

A. Kaaya

Laboratory of Waters and Environment, Department of Biology, Faculty of Sciences, 28/S, Agadir, Morocco

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M. Jana,

M. Jana

Laboratory of Phytochemistry, Department of Chemistry, Faculty of Sciences-Semlalia, P.O.B: S15, Marrakesh, Morocco

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First published: 21 December 1998

https://doi.org/10.1002/(SICI)1099-1573(199812)12:8<592::AID-PTR348>3.0.CO;2-Z

Citations: 6

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Abstract

This work examines the toxicological effects of Globularia alypum leaves and Zygophyllum gaetulum aerial parts used in the traditional treatment of diabetes mellitus in Morocco.

The LD₅₀ after oral administration of the plant infusions was higher than 10 g/kg body weight. Chronic toxicity was evaluated by analysis of biochemical and haematological parameters and by anatomo-histopathological studies. It is suggested that these plants have no toxicological effects in rats. Copyright © 1998 John Wiley & Sons, Ltd.

References

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Volume12, Issue8

December 1998

Pages 592-594

Toxicological studies on Globularia alypum and Zygophyllum gaetulum in rats

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References

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Toxicological studies on Globularia alypum and Zygophyllum gaetulum in rats

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