Symptoms of 100 patients with electromyographically verified carpal tunnel syndrome†
Corresponding Author
J. Clarke Stevens MD
Department of Neurology, Mayo Clinic Scottsdale, 13400 East Shea Boulevard, Scottsdale, Arizona, USA
Department of Neurology, Mayo Clinic Scottsdale, 13400 East Shea Boulevard, Scottsdale, Arizona, USASearch for more papers by this authorBenn E. Smith MD
Department of Neurology, Mayo Clinic Scottsdale, 13400 East Shea Boulevard, Scottsdale, Arizona, USA
Search for more papers by this authorAmy L. Weaver MS
Section of Biostatistics, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA
Search for more papers by this authorE. Peter Bosch MD
Department of Neurology, Mayo Clinic Scottsdale, 13400 East Shea Boulevard, Scottsdale, Arizona, USA
Search for more papers by this authorH. Gordon Deen Jr. MD
Department of Neurologic Surgery, Mayo Clinic Scottsdale, Scottsdale, Arizona, USA
Search for more papers by this authorJames A. Wilkens MD
Division of Regional and International Medicine, Mayo Clinic Scottsdale, Scottsdale, Arizona, USA
Search for more papers by this authorCorresponding Author
J. Clarke Stevens MD
Department of Neurology, Mayo Clinic Scottsdale, 13400 East Shea Boulevard, Scottsdale, Arizona, USA
Department of Neurology, Mayo Clinic Scottsdale, 13400 East Shea Boulevard, Scottsdale, Arizona, USASearch for more papers by this authorBenn E. Smith MD
Department of Neurology, Mayo Clinic Scottsdale, 13400 East Shea Boulevard, Scottsdale, Arizona, USA
Search for more papers by this authorAmy L. Weaver MS
Section of Biostatistics, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA
Search for more papers by this authorE. Peter Bosch MD
Department of Neurology, Mayo Clinic Scottsdale, 13400 East Shea Boulevard, Scottsdale, Arizona, USA
Search for more papers by this authorH. Gordon Deen Jr. MD
Department of Neurologic Surgery, Mayo Clinic Scottsdale, Scottsdale, Arizona, USA
Search for more papers by this authorJames A. Wilkens MD
Division of Regional and International Medicine, Mayo Clinic Scottsdale, Scottsdale, Arizona, USA
Search for more papers by this authorPresented in part at the annual meeting of the American Association of Electrodiagnostic Medicine, San Diego, CA, September 1997
Abstract
To determine the symptoms of carpal tunnel syndrome (CTS), screening evaluations were performed in 244 consecutive patients with sensory symptoms in the hand and unequivocal slowing of median nerve conduction at the wrist. This yielded 100 patients thought to have no explanation other than CTS for their upper limb complaints. These patients completed a hand symptom diagram (HSD) and questionnaire (HSQ) about their symptoms. CTS symptoms were most commonly reported in median and ulnar digits, followed by median digits only and a glove distribution. Unusual sensory patterns were reported by some patients. Based on the HSQ, paresthesias or pain proximal to the wrist occurred in 36.5% of hands. The usefulness of the HSD and HSQ for diagnosis was determined by asking three physicians, blinded to the diagnosis, to rate the likelihood of CTS in the patients with CTS and in 50 patients with other causes of upper extremity paresthesia. The sensitivities of the instruments ranged from 54.1% to 85.5%. Combining the HSD and HSQ ratings increased the range of sensitivities to 79.3% to 93.7%. © 1999 John Wiley & Sons, Inc. Muscle Nerve 22: 1448–1456, 1999
REFERENCES
- 1Bowles APJr, Asher SW, Pickett JB. Use of Tinel's sign in carpal tunnel syndrome [letter]. Ann Neurol 1983; 13: 689–690. Medline
- 2Carroll GJ. Comparison of median and radial nerve sensory latencies in the electrophysiological diagnosis of carpal tunnel syndrome. Electroencephalogr Clin Neurophysiol 1987; 68: 101–106. Medline
- 3Charles N, Vial C, Chauplannaz G, Bady B. Clinical validation of antidromic stimulation of the ring finger in early electrodiagnosis of mild carpal tunnel syndrome. Electroencephalogr Clin Neurophysiol 1990; 76: 142–147. Medline
- 4Dawson DM, Hallett M, Millender LH. Entrapment neuropathies, 2nd ed. Boston: Little, Brown; 1990.
- 5de Krom MC, Knipschild PG, Kester AD, Spaans F. Efficacy of provocative tests for diagnosis of carpal tunnel syndrome. Lancet 1990; 335: 393–395. Medline
- 6De Lean J. Transcarpal median sensory conduction: detection of latent abnormalities in mild carpal tunnel syndrome. Can J Neurol Sci 1988; 15: 388–393. Medline
- 7Doyle JR, Carroll RE. The carpal tunnel syndrome. A review of 100 patients treated surgically. Calif Med 1968; 108: 263–267. Medline
- 8Durkan JA. A new diagnostic test for carpal tunnel syndrome. J Bone Jt Surg [Am] 1991; 73: 535–538.
- 9Ferry S, Silman AJ, Pritchard T, Keenan J, Croft P. The association between different patterns of hand symptoms and objective evidence of median nerve compression: a community-based survey. Arthritis Rheum 1998; 41: 720–724. Medline
- 10Gainer JVJr, Nugent GR. Carpal tunnel syndrome: report of 430 operations. South Med J 1977; 70: 325–328. Medline
- 11Goadsby PJ, Burke D. Deficits in the function of small and large afferent fibers in confirmed cases of carpal tunnel syndrome. Muscle Nerve 1994; 17: 614–622. Medline
- 12Golding DN, Rose DM, Selvarajah K. Clinical tests for carpal tunnel syndrome: an evaluation. Br J Rheumatol 1986; 25: 388–390. Medline
- 13Gupta SK, Benstead TJ. Symptoms experienced by patients with carpal tunnel syndrome. Can J Neurol Sci 1997; 24: 338–342. Medline
- 14Hansson S. Segmental median nerve conduction measurements discriminate carpal tunnel syndrome from diabetic polyneuropathy. Muscle Nerve 1995; 18: 445–453. Medline
- 15Heller L, Ring H, Costeff H, Solzi P. Evaluation of Tinel's and Phalen's signs in diagnosis of the carpal tunnel syndrome. Eur Neurol 1986; 25: 40–42. Medline
- 16Hybbinette CH, Mannerfelt L. The carpal tunnel syndrome. A retrospective study of 400 operated patients. Acta Orthop Scand 1975; 46: 610–620. Medline
- 17Jackson DA, Clifford JC. Electrodiagnosis of mild carpal tunnel syndrome. Arch Phys Med Rehabil 1989; 70: 199–204. Medline
- 18Johnson EW. Should immediate surgery be done for carpal tunnel syndrome?—no! Muscle Nerve 1995; 18: 658–659. Medline
- 19Johnson EW, Kukla RD, Wongsam PE, Piedmont A. Sensory latencies to the ring finger: normal values and relation to carpal tunnel syndrome. Arch Phys Med Rehabil 1981; 62: 206–208. Medline
- 20Katz JN, Larson MG, Sabra A, Krarup C, Stirrat CR, Sethi R, Eaton HM, Fossel AH, Liang MH. The carpal tunnel syndrome: diagnostic utility of the history and physical examination findings. Ann Intern Med 1990; 112: 321–327. Medline
- 21Katz JN, Stirrat CR, Larson MG, Fossel AH, Eaton HM, Liang MH. A self-administered hand symptom diagram for the diagnosis and epidemiologic study of carpal tunnel syndrome. J Rheumatol 1990; 17: 1495–1498. Medline
- 22Kimura I, Ayyar DR. The carpal tunnel syndrome: electrophysiological aspects of 639 symptomatic extremities. Electromyogr Clin Neurophysiol 1985; 25: 151–164. Medline
- 23Kummel BM, Zazanis GA. Shoulder pain as the presenting complaint in carpal tunnel syndrome. Clin Orthop 1973; 92: 227–230. Medline
- 24Kuntzer T. Carpal tunnel syndrome in 100 patients: sensitivity, specificity of multi-neurophysiological procedures and estimation of axonal loss of motor, sensory and sympathetic median nerve fibers. J Neurol Sci 1994; 127: 221–229. Medline
- 25Loong SC. The carpal tunnel syndrome: a clinical and electrophysiological study of 250 patients. Clin Exp Neurol 1977; 14: 51–65. Medline
- 26Macdonell RA, Schwartz MS, Swash M. Carpal tunnel syndrome: which finger should be tested? An analysis of sensory conduction in digital branches of the median nerve. Muscle Nerve 1990; 13: 601–606. Medline
- 27Monga TN, Laidlow DM. Carpal tunnel syndrome. Measurement of sensory potentials using ring and index fingers. Am J Phys Med 1982; 61: 123–129. Medline
- 28Murga L, Moreno JM, Menendez C, Castilla JM. The carpal tunnel syndrome. Relationship between median distal motor latency and graded results of needle electromyography. Electromyogr Clin Neurophysiol 1994; 34: 377–383. Medline
- 29Nathan PA, Meadows KD, Doyle LS. Sensory segmental latency values of the median nerve for a population of normal individuals. Arch Phys Med Rehabil 1988; 69: 499–501. Medline
- 30Oswald TA, Wertsch JJ, Vennix MJ, Brooks LL, Spreitzer AM. Ulnar paresthesias as a presenting symptom of carpal tunnel “syndrome” [abstract]. Muscle Nerve 1994; 17: 1082.
- 31Pease WS, Cannell CD, Johnson EW. Median to radial latency difference test in mild carpal tunnel syndrome. Muscle Nerve 1989; 12: 905–909. Medline
- 32Phalen GS. The carpal-tunnel syndrome. Seventeen years' experience in diagnosis and treatment of six hundred fifty-four hands. J Bone Jt Surg [Am] 1966; 48: 211–228.
- 33Preston DC, Logigian EL. Lumbrical and interossei recording in carpal tunnel syndrome. Muscle Nerve 1992; 15: 1253–1257. Medline
- 34Preston DC, Logigian EL. Sensitivity of the three median-to-ulnar comparative tests in diagnosis of mild carpal tunnel syndrome [letter]. Muscle Nerve 1994; 17: 955–956. Medline
- 35Raudino F. Radial sensory nerve entrapment in carpal tunnel syndrome. Electromyogr Clin Neurophysiol 1995; 35: 201–205. Medline
- 36Rossi S, Giannini F, Passero S, Paradiso C, Battistini N, Cioni R. Sensory neural conduction of median nerve from digits and palm stimulation in carpal tunnel syndrome. Electroencephalogr Clin Neurophysiol 1994; 93: 330–334. Medline
- 37Seror P. Sensitivity of the various tests for the diagnosis of carpal tunnel syndrome. J Hand Surg [Br] 1994; 19: 725–728. Medline
- 38Silver MA, Gelberman RH, Gellman H, Rhoades CE. Carpal tunnel syndrome: associated abnormalities in ulnar nerve function and the effect of carpal tunnel release on these abnormalities. J Hand Surg [Am] 1985; 10: 710–713. Medline
- 39Stevens JC. AAEE minimonograph #26: The electrodiagnosis of carpal tunnel syndrome. Muscle Nerve 1987; 10: 99–113. Medline
- 40Stevens JC, Sun S, Beard CM, O'Fallon WM, Kurland LT. Carpal tunnel syndrome in Rochester, Minnesota, 1961 to 1980. Neurology 1988; 38: 134–138. Medline
- 41Stewart JD, Eisen A. Tinel's sign and the carpal tunnel syndrome. BMJ 1978; 2: 1125–1126.
- 42Treister MR. Entrapment neuropathies of the upper extremities [letter]. N Engl J Med 1994; 330: 1389.
- 43Uncini A, Lange DJ, Solomon M, Soliven B, Meer J, Lovelace RE. Ring finger testing in carpal tunnel syndrome: a comparative study of diagnostic utility. Muscle Nerve 1989; 12: 735–741 Medline