Volume 45, Issue 4 pp. 386-393
Original Study

Rheolytic thrombectomy in the treatment of acute limb-threatening ischemia: Immediate results and six-month follow-up of the multicenter AngioJet® registry

Jose A. Silva MD

Jose A. Silva MD

Department of Cardiology, Ochsner Clinic, New Orleans, Louisiana

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Stephen R. Ramee MD

Corresponding Author

Stephen R. Ramee MD

Department of Cardiology, Ochsner Clinic, New Orleans, Louisiana

1514 Jefferson Highway, New Orleans, LA 70121Search for more papers by this author
Tyrone J. Collins MD

Tyrone J. Collins MD

Department of Cardiology, Ochsner Clinic, New Orleans, Louisiana

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J. Stephen Jenkins MD

J. Stephen Jenkins MD

Department of Cardiology, Ochsner Clinic, New Orleans, Louisiana

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Alexandra J. Lansky MD

Alexandra J. Lansky MD

Washington Cardiology Center, Washington Hospital Center, Washington, D.C.

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Gary M. Ansel MD

Gary M. Ansel MD

Mid-Ohio Cardiology Consultants, Columbus, Ohio

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Bart L. Dolmatch MD

Bart L. Dolmatch MD

Section of Vascular and Interventional Radiology, Cleveland Clinic, Cleveland, Ohio

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Mark H. Glickman MD

Mark H. Glickman MD

Virginia Vascular Associates, Norfolk, Virginia

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Brian Stainken MD

Brian Stainken MD

Department of Vascular Radiology, Albany Medical Center, Albany, New York

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Emily Ramee MD

Emily Ramee MD

Department of Cardiology, Ochsner Clinic, New Orleans, Louisiana

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Christopher J. White MD

Christopher J. White MD

Department of Cardiology, Ochsner Clinic, New Orleans, Louisiana

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For the Possis Peripheral AngioJet Study AngioJet® Investigators

Abstract

We tested the efficacy of rheolytic thrombectomy in treating 21 patients (mean age 68 ± 12 years; 66% male) and 22 vessels (limbs) who presented to the hospital within 2 weeks of the development of limb-threatening ischemia. Fifty-two percent had contraindications to use thrombolytics, and 57% had severe comorbidities. All of the vessels were occluded with thrombus on the initial angiogram. Procedural success was achieved in 20 limbs (91%). Three patients expired in the hospital, and one expired at follow-up due to nonvascular causes. Acute limb salvage was achieved in 18 of 19 limbs (95%) in the 18 survivors, and 6-month limb salvage was achieved in 16 of 18 limbs (89%) in the 17 survivors. Rheolytic thrombectomy is effective in restoring immediate blood flow in acute limb-threatening ischemia, especially in high-risk surgical patients or patients with contraindications to thrombolytic therapy. Cathet. Cardiovasc. Diagn. 45:386–393, 1998. © 1998 Wiley-Liss, Inc.

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