Human Cancer

A population-based epidemiological study of human T-cell leukemia virus type I infection in Kin-Hu, Kinmen

Corresponding Author

Yi-Ming A. Chen

Institute of Public Health, Preparatory Office of the AIDS Research Center and Community Medicine Research Center, National Yang-Ming University, Taipei, Taiwan, Republic of China

Institute of Public Health, National Yang-Ming University, Shih-Pai, Taipei, 11221, Taiwan, Republic of China. Fax: (886)-2-822-1942Search for more papers by this author

Hui-Ching Lin,

Hui-Ching Lin

Institute of Public Health, Preparatory Office of the AIDS Research Center and Community Medicine Research Center, National Yang-Ming University, Taipei, Taiwan, Republic of China

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Pesus Chou,

Pesus Chou

Institute of Public Health, Preparatory Office of the AIDS Research Center and Community Medicine Research Center, National Yang-Ming University, Taipei, Taiwan, Republic of China

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Yi-Ming A. Chen,

Corresponding Author

Yi-Ming A. Chen

Institute of Public Health, Preparatory Office of the AIDS Research Center and Community Medicine Research Center, National Yang-Ming University, Taipei, Taiwan, Republic of China

Institute of Public Health, National Yang-Ming University, Shih-Pai, Taipei, 11221, Taiwan, Republic of China. Fax: (886)-2-822-1942Search for more papers by this author

Hui-Ching Lin,

Hui-Ching Lin

Institute of Public Health, Preparatory Office of the AIDS Research Center and Community Medicine Research Center, National Yang-Ming University, Taipei, Taiwan, Republic of China

Search for more papers by this author

Pesus Chou,

Pesus Chou

Institute of Public Health, Preparatory Office of the AIDS Research Center and Community Medicine Research Center, National Yang-Ming University, Taipei, Taiwan, Republic of China

Search for more papers by this author

First published: 1 March 1996

https://doi.org/10.1002/(SICI)1097-0215(19960301)65:5<569::AID-IJC3>3.0.CO;2-0

Citations: 3

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Abstract

Kinmen is a group of small islands located between Taiwan and Fu-Kien Province of mainland China. The general population in Kinmen are descendants of immigrants from mainland China who began arriving around 317 A.D. Since it has been reported that 0.48% of adults in Taiwan have HTLV-I infection, the decision was made to conduct a community-based epidemiological study in Kinmen to understand the origin and dissemination of HTLV-I in north-east Asia. Over 68% of residents of Kin-Hu township in Kinmen over 30 years of age participated in this study. Eight of 1,425 males and 14 of 1,595 females had HTLV-I infection. Antibody reactivities were further tested by Western blot assays with HTLV-I or HTLV-II type-specific recombinant envelope glycoproteins, and it was determined that all of those infected had HTLV-I and none had HTLV-II. Logistic regression was used for multivariate analysis. The final model indicated that the significant factors associated with HTLV-I infection in Kinmen were age and coastal residency. Age was positively correlated with HTLV-I infection. The eastern coastal area had a rate of HTLV-I infection 3.1 times higher than other areas in Kin-Hu. Further genetic analysis in Kinmen is needed to elucidate a relationship with other HTLV-I isolates in the world. © 1996 Wiley-Liss, Inc.

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Volume65, Issue5

1 March 1996

Pages 569-573

A population-based epidemiological study of human T-cell leukemia virus type I infection in Kin-Hu, Kinmen

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A population-based epidemiological study of human T-cell leukemia virus type I infection in Kin-Hu, Kinmen

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