Immune microenvironment controls the outcome of PD-1 blockade in cutaneous immune response
Tatsuya Ogawa
Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Search for more papers by this authorCorresponding Author
Yosuke Ishitsuka
Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Correspondence
Yosuke Ishitsuka, Department of Dermatology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
Email: [email protected]
Search for more papers by this authorAkimasa Saito
Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Search for more papers by this authorYoshiyuki Nakamura
Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Search for more papers by this authorRei Watanabe
Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Search for more papers by this authorNaoko Okiyama
Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Search for more papers by this authorYasuhiro Fujisawa
Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Search for more papers by this authorManabu Fujimoto
Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Search for more papers by this authorTatsuya Ogawa
Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Search for more papers by this authorCorresponding Author
Yosuke Ishitsuka
Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Correspondence
Yosuke Ishitsuka, Department of Dermatology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
Email: [email protected]
Search for more papers by this authorAkimasa Saito
Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Search for more papers by this authorYoshiyuki Nakamura
Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Search for more papers by this authorRei Watanabe
Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Search for more papers by this authorNaoko Okiyama
Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Search for more papers by this authorYasuhiro Fujisawa
Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Search for more papers by this authorManabu Fujimoto
Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Search for more papers by this author
Supporting Information
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REFERENCES
- 1Shen J, Chang J, Mendenhall M, Cherry G, Goldman JW, Kulkarni RP. Diverse cutaneous adverse eruptions caused by anti-programmed cell death-1 (PD-1) and anti-programmed cell death ligand-1 (PD-L1) immunotherapies: clinical features and management. Ther Adv Med Oncol. 2018; 10: 1758834017751634.
- 2Okazaki T, Honjo T. The PD-1-PD-L pathway in immunological tolerance. Trends Immunol. 2006; 27: 195-201.
- 3Tsushima F, Iwai H, Otsuki N, et al. Preferential contribution of B7–H1 to programmed death-1-mediated regulation of hapten-specific allergic inflammatory responses. Eur J Immunol. 2003; 33: 2773-2782.
- 4Gaide O, Emerson RO, Jiang X, et al. Common clonal origin of central and resident memory T cells following skin immunization. Nat Med. 2015; 21: 647-653.
- 5Macdonald WA, Chen Z, Gras S, et al. T cell allorecognition via molecular mimicry. Immunity. 2009; 31: 897-908.
- 6Vanderlugt CJ, Miller SD. Epitope spreading. Curr Opin Immunol. 1996; 8: 831-836.
- 7Michot JM, Bigenwald C, Champiat S, et al. Immune-related adverse events with immune checkpoint blockade: a comprehensive review. Eur J Cancer. 2016; 54: 139-148.
- 8Ansari M, Salama AD, Chitnis T, et al. The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice. J Exp Med. 2003; 198: 63-69.