Volume 11, Issue 9 pp. 2431-2439

ORIGINAL ARTICLE

Open Access

Evaluation of the 3-minute chair rise test as part of preoperative evaluation for patients with non-small cell lung cancer

Mathilde Azzi MD,

Mathilde Azzi MD

Department of Respiratory and Exercise Physiology, Rouen University Hospital, Rouen, France

Pulmonary, Thoracic Oncology and Respiratory Intensive Care Department, Rouen University Hospital, Rouen, France

Search for more papers by this author

David Debeaumont MD,

David Debeaumont MD

Department of Respiratory and Exercise Physiology, Rouen University Hospital, Rouen, France

CIC-CRB 1404, Rouen University Hospital, Rouen, France

Search for more papers by this author

Tristan Bonnevie PT, MSc,

Tristan Bonnevie PT, MSc

ADIR Association, Rouen University Hospital, Rouen, France

Normandy University UNIROUEN, UPRES EA 3830, Haute Normandie Research and Biomedical Innovation, Rouen, France

Search for more papers by this author

Bernard Aguilaniu MD, PhD,

Bernard Aguilaniu MD, PhD

Faculty of Medicine, Grenoble-Alpes University, Grenoble, France

Search for more papers by this author

Damiano Cerasuolo MD,

Damiano Cerasuolo MD

Department of Biostatistics, Rouen University Hospital, Rouen, France

Search for more papers by this author

Fairuz Boujibar PT, MSc,

Fairuz Boujibar PT, MSc

Normandy University UNIROUEN, INSERM U1096, Haute Normandie Research and Biomedical Innovation, Rouen, France

Department of Thoracic Surgery, Rouen University Hospital, Rouen, France

Search for more papers by this author

Antoine Cuvelier MD, PhD,

Antoine Cuvelier MD, PhD

Pulmonary, Thoracic Oncology and Respiratory Intensive Care Department, Rouen University Hospital, Rouen, France

Normandy University UNIROUEN, UPRES EA 3830, Haute Normandie Research and Biomedical Innovation, Rouen, France

Search for more papers by this author

Francis-Edouard Gravier PT, MSc,

Corresponding Author

Francis-Edouard Gravier PT, MSc

[email protected]

orcid.org/0000-0003-3518-2898

ADIR Association, Rouen University Hospital, Rouen, France

Normandy University UNIROUEN, UPRES EA 3830, Haute Normandie Research and Biomedical Innovation, Rouen, France

Correspondence

Francis-Edouard Gravier, ADIR Association, Rouen University Hospital, 147 Avenue du Maréchal Juin, 76230 Bois-Guillaume, France.

Tel: +33 2 35 59 29 70

Fax: +33 2 35 59 29 71

Email: [email protected]

Search for more papers by this author

Mathilde Azzi MD,

Mathilde Azzi MD

Department of Respiratory and Exercise Physiology, Rouen University Hospital, Rouen, France

Pulmonary, Thoracic Oncology and Respiratory Intensive Care Department, Rouen University Hospital, Rouen, France

Search for more papers by this author

David Debeaumont MD,

David Debeaumont MD

Department of Respiratory and Exercise Physiology, Rouen University Hospital, Rouen, France

CIC-CRB 1404, Rouen University Hospital, Rouen, France

Search for more papers by this author

Tristan Bonnevie PT, MSc,

Tristan Bonnevie PT, MSc

ADIR Association, Rouen University Hospital, Rouen, France

Normandy University UNIROUEN, UPRES EA 3830, Haute Normandie Research and Biomedical Innovation, Rouen, France

Search for more papers by this author

Bernard Aguilaniu MD, PhD,

Bernard Aguilaniu MD, PhD

Faculty of Medicine, Grenoble-Alpes University, Grenoble, France

Search for more papers by this author

Damiano Cerasuolo MD,

Damiano Cerasuolo MD

Department of Biostatistics, Rouen University Hospital, Rouen, France

Search for more papers by this author

Fairuz Boujibar PT, MSc,

Fairuz Boujibar PT, MSc

Normandy University UNIROUEN, INSERM U1096, Haute Normandie Research and Biomedical Innovation, Rouen, France

Department of Thoracic Surgery, Rouen University Hospital, Rouen, France

Search for more papers by this author

Antoine Cuvelier MD, PhD,

Antoine Cuvelier MD, PhD

Pulmonary, Thoracic Oncology and Respiratory Intensive Care Department, Rouen University Hospital, Rouen, France

Normandy University UNIROUEN, UPRES EA 3830, Haute Normandie Research and Biomedical Innovation, Rouen, France

Search for more papers by this author

Francis-Edouard Gravier PT, MSc,

Corresponding Author

Francis-Edouard Gravier PT, MSc

[email protected]

orcid.org/0000-0003-3518-2898

ADIR Association, Rouen University Hospital, Rouen, France

Normandy University UNIROUEN, UPRES EA 3830, Haute Normandie Research and Biomedical Innovation, Rouen, France

Correspondence

Francis-Edouard Gravier, ADIR Association, Rouen University Hospital, 147 Avenue du Maréchal Juin, 76230 Bois-Guillaume, France.

Tel: +33 2 35 59 29 70

Fax: +33 2 35 59 29 71

Email: [email protected]

Search for more papers by this author

First published: 08 July 2020

https://doi.org/10.1111/1759-7714.13548

Citations: 6

Share a link

Email
Wechat
Bluesky

Abstract

Background

Peak oxygen uptake ( $urn:x-wiley:00000000:media:tca13548:tca13548-math-0001$ ) measured by a cardiopulmonary exercise test (CPX) is the gold-standard for predicting surgical risk in patients with non-small cell lung cancer (NSCLC). The 3-minute chair rise test (3CRT) is a simple test requiring minimal resources. This study aimed to determine the ability of 3CRT to predict $urn:x-wiley:00000000:media:tca13548:tca13548-math-0002$ in patients with NSCLC.

Methods

Retrospective data from CPX and 3CRT carried out in 36 patients with NSCLC between March 2018 and February 2019 were included. A multivariate analysis was undertaken to derive a predictive $urn:x-wiley:00000000:media:tca13548:tca13548-math-0061$ equation based on performance on the 3CRT. In addition, sensitivity-specificity analysis was carried out to estimate a threshold 3CRT value for the prediction of $urn:x-wiley:00000000:media:tca13548:tca13548-math-0003$ ≥ 15 mL/kg/minute.

Results

The following equation was obtained: $urn:x-wiley:00000000:media:tca13548:tca13548-math-0004$ predicted = (0.04765 × FEV1) - (0.207 59 × BMI) - (0.115 89 × age) + (0.386 09 × vertical distance) + 16.628 69; r² = 0.75, P < 0.01. The bias between the $urn:x-wiley:00000000:media:tca13548:tca13548-math-0005$ values predicted and measured during CPX was 0.0 ± 1.7 mL/kg/minute (95% limits of agreement [−3.5 to 3.5]). A performance ≥49 chair rises predicted $urn:x-wiley:00000000:media:tca13548:tca13548-math-0006$ ≥ 15 mL/kg/minute with a sensitivity of 0.75 and a specificity of 0.81.

Conclusions

The level of error in the prediction of $urn:x-wiley:00000000:media:tca13548:tca13548-math-0062$ from 3CRT performance was too great to recommend that 3CRT should replace CPX as the sole measurement of $urn:x-wiley:00000000:media:tca13548:tca13548-math-0007$ . Nevertheless, the 3CRT could help to identify those patients that require CPX prior to lung resection surgery for NSCLC, larger prospective study is needed to confirm this hypothesis.

Key points

Significant findings of the study

Cardiopulmonary exercise tests can stratify the surgical risk. Prediction of the peak oxygen uptake ( $urn:x-wiley:00000000:media:tca13548:tca13548-math-0008$ ) value from the 3CRT yields an unacceptable level of error. However, a performance of 49 chair rises or more during the 3CRT could indicate a $urn:x-wiley:00000000:media:tca13548:tca13548-math-0009$ ≥ 15 mL / kg / minute.

What this study adds

The 3CRT is a useful screening tool to determine the necessity for a comprehensive cardiopulmonary exercise test, whose access is limited in clinical practice. It could also allow early screening of patients requiring specific prehabilitation programs.

Supporting Information

References

1Howington JA, Blum MG, Chang AC, Balekian AA, Murthy SC. Treatment of stage I and II non-small cell lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 2013; 143(5 Suppl):e278S–e313S.
10.1378/chest.12-2359
CAS PubMed Web of Science® Google Scholar
2Grose D, Morrison DS, Devereux G et al. Comorbidities in lung cancer: Prevalence, severity and links with socioeconomic status and treatment. Postgrad Med J 2014; 90 (1064): 305–10.
10.1136/postgradmedj-2013-132186
PubMed Web of Science® Google Scholar
3Gagne S, McIsaac DI. Modifiable risk factors for patients undergoing lung cancer surgery and their optimization: A review. J Thorac Dis 2018; 10 (Suppl 32): S3761–s3772.
10.21037/jtd.2018.10.04
PubMed Web of Science® Google Scholar
4Lugg ST, Agostini PJ, Tikka T et al. Long-term impact of developing a postoperative pulmonary complication after lung surgery. Thorax 2016; 71 (2): 171–6.
10.1136/thoraxjnl-2015-207697
PubMed Web of Science® Google Scholar
5Benzo R, Kelley GA, Recchi L, Hofman A, Sciurba F. Complications of lung resection and exercise capacity: A meta-analysis. Respir Med 2007; 101 (8): 1790–7.
10.1016/j.rmed.2007.02.012
PubMed Web of Science® Google Scholar
6Brunelli A, Belardinelli R, Refai M et al. Peak oxygen consumption during cardiopulmonary exercise test improves risk stratification in candidates to major lung resection. Chest 2009; 135 (5): 1260–7.
10.1378/chest.08-2059
PubMed Web of Science® Google Scholar
7Brunelli A, Kim AW, Berger KI, Addrizzo-Harris DJ. Physiologic evaluation of the patient with lung cancer being considered for resectional surgery: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 2013; 143(5 Suppl):e166S–e190S. https://doi.org/10.1378/chest.12-2395.
10.1378/chest.12-2395
CAS PubMed Web of Science® Google Scholar
8Benzo RP, Sciurba FC. Oxygen consumption, shuttle walking test and the evaluation of lung resection. Respiration 2010; 80 (1): 19–23.
10.1159/000235543
PubMed Web of Science® Google Scholar
9Brunelli A, Refai M, Xiume F et al. Performance at symptom-limited stair-climbing test is associated with increased cardiopulmonary complications, mortality, and costs after major lung resection. Ann Thorac Surg 2008; 86 (1): 240–7; discussion 247-248.
10.1016/j.athoracsur.2008.03.025
PubMed Web of Science® Google Scholar
10Brunelli A, Xiume F, Refai M et al. Peak oxygen consumption measured during the stair-climbing test in lung resection candidates. Respiration 2010; 80 (3): 207–11.
10.1159/000279331
PubMed Web of Science® Google Scholar
11 British Thoracic Society, Society of Cardiothoracic Surgeons of Great Britain and Ireland Working Party. BTS guidelines: Guidelines on the selection of patients with lung cancer for surgery. Thorax 2001; 56 (2): 89–108.
10.1136/thorax.56.2.89
PubMed Web of Science® Google Scholar
12Brunelli A, Charloux A, Bolliger CT et al. ERS/ESTS clinical guidelines on fitness for radical therapy in lung cancer patients (surgery and chemo-radiotherapy). Eur Respir J 2009; 34 (1): 17–41.
10.1183/09031936.00184308
CAS PubMed Web of Science® Google Scholar
13Aguilaniu B, Roth H, Gonzalez-Bermejo J et al. A simple semipaced 3-minute chair rise test for routine exercise tolerance testing in COPD. Int J Chron Obstruct Pulmon Dis 2014; 9: 1009–19.
10.2147/COPD.S59855
PubMed Web of Science® Google Scholar
14Miller MR, Crapo R, Hankinson J et al. General considerations for lung function testing. Eur Respir J 2005; 26 (1): 153–61.
10.1183/09031936.05.00034505
CAS PubMed Web of Science® Google Scholar
15Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault JC. Lung volumes and forced ventilatory flows. Report working party standardization of lung function tests, European Community for Steel and Coal Official Statement of the European Respiratory Society. Eur Respir J Suppl 1993; 16: 5–40.
10.1183/09041950.005s1693
CAS PubMed Google Scholar
16 American Thoracic Society, American College of Chest Physicians. ATS/ACCP statement on cardiopulmonary exercise testing. Am J Respir Crit Care Med 2003; 167 (2): 211–77.
10.1164/rccm.167.2.211
PubMed Web of Science® Google Scholar
17Siegel RL, Miller KD, Jemal A. Cancer statistics, 2019. CA Cancer J Clin 2019; 69 (1): 7–34.
10.3322/caac.21551
PubMed Web of Science® Google Scholar
18Zanini A, Aiello M, Cherubino F et al. The one repetition maximum test and the sit-to-stand test in the assessment of a specific pulmonary rehabilitation program on peripheral muscle strength in COPD patients. Int J Chron Obstruct Pulmon Dis 2015; 10: 2423–30.
10.2147/COPD.S91176
PubMed Web of Science® Google Scholar
19Ozalevli S, Ozden A, Itil O, Akkoclu A. Comparison of the sit-to-stand test with 6 min walk test in patients with chronic obstructive pulmonary disease. Respir Med 2007; 101 (2): 286–93.
10.1016/j.rmed.2006.05.007
CAS PubMed Web of Science® Google Scholar
20Reychler G, Boucard E, Peran L et al. One minute sit-to-stand test is an alternative to 6MWT to measure functional exercise performance in COPD patients. Clin Respir J 2018; 12 (3): 1247–56.
10.1111/crj.12658
PubMed Web of Science® Google Scholar
21Puente-Maestu L, Sanz ML, Sanz P, Nunez A, Gonzalez F, Whipp BJ. Reproducibility of the parameters of the on-transient cardiopulmonary responses during moderate exercise in patients with chronic obstructive pulmonary disease. Eur J Appl Physiol 2001; 85 (5): 434–41.
10.1007/s004210100486
CAS PubMed Web of Science® Google Scholar
22Pessoa BV, Beltrame T, Di Lorenzo VA, Catai AM, Borghi-Silva A, Jamami M. COPD patients' oxygen uptake and heart rate on-kinetics at cycle-ergometer: Correlation with their predictors of severity. Braz J Phys Ther 2013; 17 (2): 152–62.
10.1590/S1413-35552012005000073
PubMed Web of Science® Google Scholar
23Clark JM, Marrufo AS, Kozower BD et al. Cardiopulmonary testing before lung resection: What are thoracic surgeons doing? Ann Thorac Surg 2019; 108 (4): 1006–12.
10.1016/j.athoracsur.2019.04.057
PubMed Web of Science® Google Scholar
24Levesque J, Antoniadis A, Li PZ et al. Minimal clinically important difference of 3-minute chair rise test and the DIRECT questionnaire after pulmonary rehabilitation in COPD patients. Int J Chron Obstruct Pulmon Dis 2019; 14: 261–9.
10.2147/COPD.S187567
PubMed Google Scholar
25Zhang Y, Hedo R, Rivera A, Rull R, Richardson S, Tu X. Post hoc power analysis: Is it an informative and meaningful analysis? General Psychiatry 2019; 32: e100069.
10.1136/gpsych-2019-100069
PubMed Web of Science® Google Scholar

Citing Literature

Volume11, Issue9

September 2020

Pages 2431-2439