An Improved Protocol for Synthesis of 3-Substituted 5-Arylidene-2-thiohydantoins: Two-step Procedure Alternative to Classical Methods
Olga Yu Kuznetsova
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119992 Russia
Search for more papers by this authorRoman L. Antipin
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119992 Russia
Search for more papers by this authorAnna V. Udina
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119992 Russia
Search for more papers by this authorOlga O. Krasnovskaya
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119992 Russia
Search for more papers by this authorElena K. Beloglazkina
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119992 Russia
Search for more papers by this authorVladimir I. Terenin
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119992 Russia
Search for more papers by this authorVictor E. Koteliansky
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119992 Russia
Search for more papers by this authorNikolay V. Zyk
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119992 Russia
Search for more papers by this authorCorresponding Author
Alexander G. Majouga
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119992 Russia
National University of Science and Technology MISiS, Leninsky Ave 4, Moscow, 119049 Russia
E-mail: [email protected]Search for more papers by this authorOlga Yu Kuznetsova
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119992 Russia
Search for more papers by this authorRoman L. Antipin
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119992 Russia
Search for more papers by this authorAnna V. Udina
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119992 Russia
Search for more papers by this authorOlga O. Krasnovskaya
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119992 Russia
Search for more papers by this authorElena K. Beloglazkina
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119992 Russia
Search for more papers by this authorVladimir I. Terenin
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119992 Russia
Search for more papers by this authorVictor E. Koteliansky
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119992 Russia
Search for more papers by this authorNikolay V. Zyk
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119992 Russia
Search for more papers by this authorCorresponding Author
Alexander G. Majouga
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119992 Russia
National University of Science and Technology MISiS, Leninsky Ave 4, Moscow, 119049 Russia
E-mail: [email protected]Search for more papers by this authorAbstract
A novel method for the direct synthesis of 5-arylidene-2-thiohydantoins from thioureas and aromatic aldehydes in the presence of base in ethanol was developed. Application of this efficient method allowed preparing thiohydantoins, which are difficult to synthesis by traditional methods.
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