Volume 10, Issue 12 p. 1562
Cover Picture
Free Access

Inside Cover: FSOCA-induced switchable footpad skin optical clearing window for blood flow and cell imaging in vivo (J. Biophotonics 12/2017)

Rui Shi

Rui Shi

Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics (WNLO), Huazhong University of Science and Technology (HUST), 1037 Luoyu Road, Wuhan, 430074, Hubei P. R. China

Key Laboratory of Biomedical Photonics, HUST, Ministry of Education, 1037 Luoyu Road, Wuhan, 430074, Hubei P. R. China

Hubei Bioinformatics and Bioimaging Key Laboratory, Department of Biomedical Engineering, HUST, 1037 Luoyu Road, Wuhan, 430074, Hubei P. R. China

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Wei Feng

Wei Feng

Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics (WNLO), Huazhong University of Science and Technology (HUST), 1037 Luoyu Road, Wuhan, 430074, Hubei P. R. China

Key Laboratory of Biomedical Photonics, HUST, Ministry of Education, 1037 Luoyu Road, Wuhan, 430074, Hubei P. R. China

Hubei Bioinformatics and Bioimaging Key Laboratory, Department of Biomedical Engineering, HUST, 1037 Luoyu Road, Wuhan, 430074, Hubei P. R. China

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Chao Zhang

Chao Zhang

Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics (WNLO), Huazhong University of Science and Technology (HUST), 1037 Luoyu Road, Wuhan, 430074, Hubei P. R. China

Key Laboratory of Biomedical Photonics, HUST, Ministry of Education, 1037 Luoyu Road, Wuhan, 430074, Hubei P. R. China

Hubei Bioinformatics and Bioimaging Key Laboratory, Department of Biomedical Engineering, HUST, 1037 Luoyu Road, Wuhan, 430074, Hubei P. R. China

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Zhihong Zhang

Zhihong Zhang

Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics (WNLO), Huazhong University of Science and Technology (HUST), 1037 Luoyu Road, Wuhan, 430074, Hubei P. R. China

Key Laboratory of Biomedical Photonics, HUST, Ministry of Education, 1037 Luoyu Road, Wuhan, 430074, Hubei P. R. China

Hubei Bioinformatics and Bioimaging Key Laboratory, Department of Biomedical Engineering, HUST, 1037 Luoyu Road, Wuhan, 430074, Hubei P. R. China

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Dan Zhu

Corresponding Author

Dan Zhu

Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics (WNLO), Huazhong University of Science and Technology (HUST), 1037 Luoyu Road, Wuhan, 430074, Hubei P. R. China

Key Laboratory of Biomedical Photonics, HUST, Ministry of Education, 1037 Luoyu Road, Wuhan, 430074, Hubei P. R. China

Hubei Bioinformatics and Bioimaging Key Laboratory, Department of Biomedical Engineering, HUST, 1037 Luoyu Road, Wuhan, 430074, Hubei P. R. China

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First published: 05 December 2017

Graphical Abstract

An innovative footpad skin optical clearing agent (FSOCA) has been developed to make the footpad skin transparent with topical treatment, and saline can make the footpad skin recovery. Cover figures show the switchable window permits various optical image to access to cutaneous blood flow with higher contrast, and to cell from deeper depth. The stable distribution and morphological structure of monocyte demonstrates repeated FSOCA treatment could not induce inflammation. Further details can be found in the article by Rui Shi et al. on pp. 1647–1656.

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