Yellow-Fluorescence Carbon Dots Employed for pH Sensing and Detection of Tigecycline†
Jingwen Zhao
College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715 China
Chongqing Academy of Metrology and Quality Inspection, Chongqing, 401121 China
Search for more papers by this authorJunchen Wang
College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715 China
Search for more papers by this authorLinggao Zeng
NMPA Key Laboratory for Quality Monitoring of Narcotic Drugs and Psychotropic Substances, Chongqing Institute for Food and Drug Control, Chongqing, 401121 China
Search for more papers by this authorCorresponding Author
Sen Zhou
Chongqing Academy of Metrology and Quality Inspection, Chongqing, 401121 China
E-mail: [email protected]; [email protected]Search for more papers by this authorCorresponding Author
Xiaoming Yang
College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715 China
NMPA Key Laboratory for Quality Monitoring of Narcotic Drugs and Psychotropic Substances, Chongqing Institute for Food and Drug Control, Chongqing, 401121 China
E-mail: [email protected]; [email protected]Search for more papers by this authorJingwen Zhao
College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715 China
Chongqing Academy of Metrology and Quality Inspection, Chongqing, 401121 China
Search for more papers by this authorJunchen Wang
College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715 China
Search for more papers by this authorLinggao Zeng
NMPA Key Laboratory for Quality Monitoring of Narcotic Drugs and Psychotropic Substances, Chongqing Institute for Food and Drug Control, Chongqing, 401121 China
Search for more papers by this authorCorresponding Author
Sen Zhou
Chongqing Academy of Metrology and Quality Inspection, Chongqing, 401121 China
E-mail: [email protected]; [email protected]Search for more papers by this authorCorresponding Author
Xiaoming Yang
College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715 China
NMPA Key Laboratory for Quality Monitoring of Narcotic Drugs and Psychotropic Substances, Chongqing Institute for Food and Drug Control, Chongqing, 401121 China
E-mail: [email protected]; [email protected]Search for more papers by this authorDedicated to the Special Issue of Carbon Dots Based Functional Materials.
Comprehensive Summary
Long-wavelength fluorescence carbon dots (CDs) show great importance in multiple fields, especially for the biochemical sensing. Here, we proposed one type of CDs doped with nitrogen and sulfur through the hydrothermal method, which exhibited obvious yellow-fluorescence in aqueous solution. Importantly, the fluorescence intensity of CDs decreased with pH decreasing in the acidic range, thus a linear relationship between pH and fluorescence intensity was established, exhibiting the potential of pH sensing. Additionally, introducing tigecycline into CDs resulted in their decreased fluorescence, thus, we further established a strategy of detecting tigecycline with the concentration range of 200 μM to 7 nM. Meanwhile, we elucidated the static quenching as the major mechanism for CDs responding tigecycline, which was induced by the formed new complex between CDs and tigecycline. Furthermore, the practicality of the method was verified by examining the recovery of tigecycline in the actual lake-water samples.
Supporting Information
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Appendix S1: Supporting Information |
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