Recent Advances
Recent Advances in Nanopore Sensing†
Mengjie Cui,
Yaxian Ge,
Xiao Zhuge,
Xin Zhou,
Dongmei Xi,
Shusheng Zhang,
Mengjie Cui
Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers, College of Chemistry and Chemical Engineering, Linyi University, Linyi, Shandong, 276005 China
M.C. and Y.G. contributed equally to this work.
Search for more papers by this authorYaxian Ge
Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers, College of Chemistry and Chemical Engineering, Linyi University, Linyi, Shandong, 276005 China
M.C. and Y.G. contributed equally to this work.
Search for more papers by this authorXiao Zhuge
Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers, College of Chemistry and Chemical Engineering, Linyi University, Linyi, Shandong, 276005 China
Search for more papers by this authorXin Zhou
Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers, College of Chemistry and Chemical Engineering, Linyi University, Linyi, Shandong, 276005 China
Search for more papers by this authorCorresponding Author
Dongmei Xi
Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers, College of Chemistry and Chemical Engineering, Linyi University, Linyi, Shandong, 276005 China
*E-mail: [email protected]; [email protected]Search for more papers by this authorCorresponding Author
Shusheng Zhang
Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers, College of Chemistry and Chemical Engineering, Linyi University, Linyi, Shandong, 276005 China
*E-mail: [email protected]; [email protected]Search for more papers by this authorMengjie Cui,
Yaxian Ge,
Xiao Zhuge,
Xin Zhou,
Dongmei Xi,
Shusheng Zhang,
Mengjie Cui
Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers, College of Chemistry and Chemical Engineering, Linyi University, Linyi, Shandong, 276005 China
M.C. and Y.G. contributed equally to this work.
Search for more papers by this authorYaxian Ge
Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers, College of Chemistry and Chemical Engineering, Linyi University, Linyi, Shandong, 276005 China
M.C. and Y.G. contributed equally to this work.
Search for more papers by this authorXiao Zhuge
Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers, College of Chemistry and Chemical Engineering, Linyi University, Linyi, Shandong, 276005 China
Search for more papers by this authorXin Zhou
Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers, College of Chemistry and Chemical Engineering, Linyi University, Linyi, Shandong, 276005 China
Search for more papers by this authorCorresponding Author
Dongmei Xi
Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers, College of Chemistry and Chemical Engineering, Linyi University, Linyi, Shandong, 276005 China
*E-mail: [email protected]; [email protected]Search for more papers by this authorCorresponding Author
Shusheng Zhang
Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers, College of Chemistry and Chemical Engineering, Linyi University, Linyi, Shandong, 276005 China
*E-mail: [email protected]; [email protected]Search for more papers by this author†
Dedicated to the Special Issue of In Situ Target Biomolecule Analysis in Confined Nanospace.
Abstract
Nanopore sensing is developing into a powerful label-free approach to investigate the features of biomolecules at the single-molecule level. When a charged molecule is captured within a nanopore, it modulates the ionic current, which can be recorded in real time to reveal the properties of the target molecule. To date, nanopores have been used to sense a variety of analytes, including DNA, RNA, proteins, enzymes, small molecules, cancer cells, and metal ions, and can also provide information on biomolecular structures. In this review, we highlight the progress made in nanopore sensing over the past five years (2016—2020), and provide an outlook on future developments and directions in the field
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