Full Paper
Application of Heteropolyacids as Heterogeneous and Recyclable Catalysts for One-Pot Synthesis of 3-Cyanopyridine Derivatives
Abstract
A simple, clean and environmentally benign route to the synthesis of 3-cyanopyridines is described via a one-pot multi-component reaction of 3,4-dimethoxyacetophenone, malonitrile or ethylcyanoacetate, aldehyde and ammonium acetate using heteropolyacids as heterogeneous and recyclable catalysts in very good yields.
