Designing Printable Medicinal Products: Solvent System and Carrier-Substrate Screening
Dhara Raijada
University of Copenhagen, Faculty of Health and Medical Sciences, Department of Pharmacy, Copenhagen, Denmark.
Search for more papers by this authorNatalja Genina
Abo Akademi University, Department of Biosciences, Pharmaceutical Sciences Laboratory, Turku, Finland.
Search for more papers by this authorDaniela Fors
Abo Akademi University, Laboratory of Physical Chemistry, Center of Excellence for Functional Materials, Turku, Finland.
Search for more papers by this authorErik Wisaeus
Danish Technological Institute, Center for Nano- and Microtechnology, Taastrup, Denmark.
Search for more papers by this authorJouko Peltonen
Abo Akademi University, Laboratory of Physical Chemistry, Center of Excellence for Functional Materials, Turku, Finland.
Search for more papers by this authorJukka Rantanen
University of Copenhagen, Faculty of Health and Medical Sciences, Department of Pharmacy, Copenhagen, Denmark.
Search for more papers by this authorNiklas Sandler
Abo Akademi University, Department of Biosciences, Pharmaceutical Sciences Laboratory, Turku, Finland.
Search for more papers by this authorDhara Raijada
University of Copenhagen, Faculty of Health and Medical Sciences, Department of Pharmacy, Copenhagen, Denmark.
Search for more papers by this authorNatalja Genina
Abo Akademi University, Department of Biosciences, Pharmaceutical Sciences Laboratory, Turku, Finland.
Search for more papers by this authorDaniela Fors
Abo Akademi University, Laboratory of Physical Chemistry, Center of Excellence for Functional Materials, Turku, Finland.
Search for more papers by this authorErik Wisaeus
Danish Technological Institute, Center for Nano- and Microtechnology, Taastrup, Denmark.
Search for more papers by this authorJouko Peltonen
Abo Akademi University, Laboratory of Physical Chemistry, Center of Excellence for Functional Materials, Turku, Finland.
Search for more papers by this authorJukka Rantanen
University of Copenhagen, Faculty of Health and Medical Sciences, Department of Pharmacy, Copenhagen, Denmark.
Search for more papers by this authorNiklas Sandler
Abo Akademi University, Department of Biosciences, Pharmaceutical Sciences Laboratory, Turku, Finland.
Search for more papers by this authorAbstract
More flexible yet robust manufacturing solutions are needed in the pharmaceutical industry. Tablet compaction is no longer the obvious choice for commercial-scale processing of innovative drug delivery systems. Engineering solutions have gained wide attention in the pharmaceutical industry. Technical innovations within printing are considerable solutions for future product design. Printable medicinal products of a model compound are designed and an analytical approach for imaging the model compound in the printed medicinal products is investigated. The potential implications of using a unique combination of ink solution and carrier-substrate for designing a specific crystallization process and future directions towards continuous manufacturing of personalized medicinal products are discussed.
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