Volume 25, Issue 5 pp. 366-373

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Synthesis, microwave-promoted catalytic activity in Suzuki–Miyaura cross-coupling reactions and antimicrobial properties of novel benzimidazole salts bearing trimethylsilyl group

Ülkü Yılmaz,

Ülkü Yılmaz

İnönü University, Faculty of Science and Arts, Department of Chemistry, 44280 Malatya, Turkey

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Hasan Küçükbay,

Corresponding Author

Hasan Küçükbay

[email protected]

İnönü University, Faculty of Science and Arts, Department of Chemistry, 44280 Malatya, Turkey

İnönü University, Faculty of Science and Arts, Department of Chemistry, 44280 Malatya, Turkey.Search for more papers by this author

Nihat Şireci,

Nihat Şireci

Adıyaman University, Faculty of Education, 02040 Adıyaman, Turkey

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Mehmet Akkurt,

Mehmet Akkurt

Erciyes University, Faculty of Sciences, Department of Physics, 38039 Kayseri, Turkey

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Selami Günal,

Selami Günal

İnönü University, Faculty of Medicine, Department of Microbiology, 44280 Malatya, Turkey

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Rıza Durmaz,

Rıza Durmaz

İnönü University, Faculty of Medicine, Department of Microbiology, 44280 Malatya, Turkey

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M. Nawaz Tahir,

M. Nawaz Tahir

University of Sargodha, Department of Physics, Sargodha, Pakistan

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Ülkü Yılmaz,

Ülkü Yılmaz

İnönü University, Faculty of Science and Arts, Department of Chemistry, 44280 Malatya, Turkey

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Hasan Küçükbay,

Corresponding Author

Hasan Küçükbay

[email protected]

İnönü University, Faculty of Science and Arts, Department of Chemistry, 44280 Malatya, Turkey

İnönü University, Faculty of Science and Arts, Department of Chemistry, 44280 Malatya, Turkey.Search for more papers by this author

Nihat Şireci,

Nihat Şireci

Adıyaman University, Faculty of Education, 02040 Adıyaman, Turkey

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Mehmet Akkurt,

Mehmet Akkurt

Erciyes University, Faculty of Sciences, Department of Physics, 38039 Kayseri, Turkey

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Selami Günal,

Selami Günal

İnönü University, Faculty of Medicine, Department of Microbiology, 44280 Malatya, Turkey

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Rıza Durmaz,

Rıza Durmaz

İnönü University, Faculty of Medicine, Department of Microbiology, 44280 Malatya, Turkey

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M. Nawaz Tahir,

M. Nawaz Tahir

University of Sargodha, Department of Physics, Sargodha, Pakistan

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First published: 04 April 2011

https://doi.org/10.1002/aoc.1772

Citations: 29

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Abstract

A mixture of benzimidazole salts (2–7), Pd(OAc)₂ and K₂CO₃ in DMF–H₂O catalyzes the Suzuki–Miyaura cross-coupling reactions promoted by microwave irradiation resulting in high yield within a short time. In particular, the yield of the Suzuki–Miyaura reactions with aryl bromides was found to be nearly quantitative. The synthesized benzimidazole salts (2–7) were identified by ¹H-¹³C, NMR, IR spectroscopic methods and microanalysis. The molecular structure of 1 was determined by X-ray crystallography. The antibacterial and antifungal activities of the novel benzimidazole derivatives (1–7) were also tested against standard strains. Copyright © 2011 John Wiley & Sons, Ltd.

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Volume25, Issue5

May 2011

Pages 366-373

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aoc_1772_sm_suppinfosir1.tif4.6 KB	Supporting Information
aoc_1772_sm_suppdatainfo.cif51.8 KB	Supporting Information

Synthesis, microwave-promoted catalytic activity in Suzuki–Miyaura cross-coupling reactions and antimicrobial properties of novel benzimidazole salts bearing trimethylsilyl group

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Synthesis, microwave-promoted catalytic activity in Suzuki–Miyaura cross-coupling reactions and antimicrobial properties of novel benzimidazole salts bearing trimethylsilyl group

Abstract

Supporting Information

References

Citing Literature

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