Minireview
Fenestranes in Synthesis: Unique and Highly Inspiring Scaffolds
Correction(s) for this article
-
Corrigendum: Fenestranes in Synthesis: Unique and Highly Inspiring Scaffolds
- Volume 53Issue 4Angewandte Chemie International Edition
- pages: 911-911
- First Published online: January 21, 2014
Dr. Aicha Boudhar,
Dr. Mélanie Charpenay,
Dr. Gaëlle Blond,
Dr. Jean Suffert,
Dr. Aicha Boudhar
Faculté de Pharmacie, Université de Strasbourg, UMR 7200 CNRS/UDS, 74 Route du Rhin, Strasbourg (France) http://www-chimie.u-strasbg.fr/∼lsb/
Search for more papers by this authorDr. Mélanie Charpenay
Faculté de Pharmacie, Université de Strasbourg, UMR 7200 CNRS/UDS, 74 Route du Rhin, Strasbourg (France) http://www-chimie.u-strasbg.fr/∼lsb/
Search for more papers by this authorDr. Gaëlle Blond
Faculté de Pharmacie, Université de Strasbourg, UMR 7200 CNRS/UDS, 74 Route du Rhin, Strasbourg (France) http://www-chimie.u-strasbg.fr/∼lsb/
Search for more papers by this authorCorresponding Author
Dr. Jean Suffert
Faculté de Pharmacie, Université de Strasbourg, UMR 7200 CNRS/UDS, 74 Route du Rhin, Strasbourg (France) http://www-chimie.u-strasbg.fr/∼lsb/
Faculté de Pharmacie, Université de Strasbourg, UMR 7200 CNRS/UDS, 74 Route du Rhin, Strasbourg (France) http://www-chimie.u-strasbg.fr/∼lsb/===Search for more papers by this authorDr. Aicha Boudhar,
Dr. Mélanie Charpenay,
Dr. Gaëlle Blond,
Dr. Jean Suffert,
Dr. Aicha Boudhar
Faculté de Pharmacie, Université de Strasbourg, UMR 7200 CNRS/UDS, 74 Route du Rhin, Strasbourg (France) http://www-chimie.u-strasbg.fr/∼lsb/
Search for more papers by this authorDr. Mélanie Charpenay
Faculté de Pharmacie, Université de Strasbourg, UMR 7200 CNRS/UDS, 74 Route du Rhin, Strasbourg (France) http://www-chimie.u-strasbg.fr/∼lsb/
Search for more papers by this authorDr. Gaëlle Blond
Faculté de Pharmacie, Université de Strasbourg, UMR 7200 CNRS/UDS, 74 Route du Rhin, Strasbourg (France) http://www-chimie.u-strasbg.fr/∼lsb/
Search for more papers by this authorCorresponding Author
Dr. Jean Suffert
Faculté de Pharmacie, Université de Strasbourg, UMR 7200 CNRS/UDS, 74 Route du Rhin, Strasbourg (France) http://www-chimie.u-strasbg.fr/∼lsb/
Faculté de Pharmacie, Université de Strasbourg, UMR 7200 CNRS/UDS, 74 Route du Rhin, Strasbourg (France) http://www-chimie.u-strasbg.fr/∼lsb/===Search for more papers by this authorGraphical Abstract
Highly strained: Four condensed cycles and a distorted tetracoordinated carbon center with bond angles greater than the regular 109.4° make the scaffold of fenestranes quite unique. A definition and nomenclature of these scaffolds is followed by a detailed overview over recent syntheses of these strained molecules, including their impact on the study of planar tetracoordinate carbon atoms.
Abstract
The scaffold of fenestranes is quite unique, as it contains four condensed cycles and a distorted tetracoordinated central carbon atom with bond angles greater than the regular 109°28“. In this Minireview, a detailed overview on the developments regarding this compound class, including their synthesis, is given for the time period since 2006. In the past years, natural products that belong to the class of heterofenestranes have been isolated and their syntheses will also be discussed.
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