Self-Propelled Polymer-Based Multilayer Nanorockets for Transportation and Drug Release†
Zhiguang Wu
Key Lab for Microsystems and Microstructure Manufacturing, The Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080 (China)
Search for more papers by this authorYingjie Wu
Key Lab for Microsystems and Microstructure Manufacturing, The Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080 (China)
Search for more papers by this authorWenping He
Key Lab for Microsystems and Microstructure Manufacturing, The Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080 (China)
Search for more papers by this authorDr. Xiankun Lin
Key Lab for Microsystems and Microstructure Manufacturing, The Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080 (China)
Search for more papers by this authorProf. Jianmin Sun
Key Lab for Microsystems and Microstructure Manufacturing, The Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080 (China)
Search for more papers by this authorCorresponding Author
Prof. Qiang He
Key Lab for Microsystems and Microstructure Manufacturing, The Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080 (China)
Key Lab for Microsystems and Microstructure Manufacturing, The Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080 (China)Search for more papers by this authorZhiguang Wu
Key Lab for Microsystems and Microstructure Manufacturing, The Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080 (China)
Search for more papers by this authorYingjie Wu
Key Lab for Microsystems and Microstructure Manufacturing, The Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080 (China)
Search for more papers by this authorWenping He
Key Lab for Microsystems and Microstructure Manufacturing, The Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080 (China)
Search for more papers by this authorDr. Xiankun Lin
Key Lab for Microsystems and Microstructure Manufacturing, The Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080 (China)
Search for more papers by this authorProf. Jianmin Sun
Key Lab for Microsystems and Microstructure Manufacturing, The Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080 (China)
Search for more papers by this authorCorresponding Author
Prof. Qiang He
Key Lab for Microsystems and Microstructure Manufacturing, The Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080 (China)
Key Lab for Microsystems and Microstructure Manufacturing, The Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080 (China)Search for more papers by this authorWe thank Prof. J. B. Li and Prof. H. Möhwald for their helpful discussions. This work was supported by the National Nature Science Foundation of China (91027045 and 21103034), the 100-talent Program of HIT, and the New Century Excellent Talent Program (NCET-11-0800).
Graphical Abstract
Nanotransporters: Self-assembled polymer multilayer nanorockets based on a template-assisted layer-by-layer technique can self-propel by chemical power, namely hydrogen peroxide degradation. They can perform drug loading, targeted transportation, and triggered drug release by an external physical stimuli in a controlled manner.
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