An Intermolecular Palladium-Catalyzed Diamination of Unactivated Alkenes†
Dr. Álvaro Iglesias
Institute of Chemical Research of Catalonia (ICIQ), Av. Països Catalans 16, 43007 Tarragona (Spain), Fax: (+34) 977-920-224 http://www.iciq.es
Search for more papers by this authorDr. Edwin G. Pérez
Institute of Chemical Research of Catalonia (ICIQ), Av. Països Catalans 16, 43007 Tarragona (Spain), Fax: (+34) 977-920-224 http://www.iciq.es
Permanent address: Facultad de Química, Pontificia Universidad Católica de Chile, Vicuña Mackenna 4860, Casilla 306, Correo 22, Santiago (Chile)
Search for more papers by this authorProf. Dr. Kilian Muñiz
Institute of Chemical Research of Catalonia (ICIQ), Av. Països Catalans 16, 43007 Tarragona (Spain), Fax: (+34) 977-920-224 http://www.iciq.es
Search for more papers by this authorDr. Álvaro Iglesias
Institute of Chemical Research of Catalonia (ICIQ), Av. Països Catalans 16, 43007 Tarragona (Spain), Fax: (+34) 977-920-224 http://www.iciq.es
Search for more papers by this authorDr. Edwin G. Pérez
Institute of Chemical Research of Catalonia (ICIQ), Av. Països Catalans 16, 43007 Tarragona (Spain), Fax: (+34) 977-920-224 http://www.iciq.es
Permanent address: Facultad de Química, Pontificia Universidad Católica de Chile, Vicuña Mackenna 4860, Casilla 306, Correo 22, Santiago (Chile)
Search for more papers by this authorProf. Dr. Kilian Muñiz
Institute of Chemical Research of Catalonia (ICIQ), Av. Països Catalans 16, 43007 Tarragona (Spain), Fax: (+34) 977-920-224 http://www.iciq.es
Search for more papers by this authorWe thank Fundación ICIQ, the Consolider INTECAT 2010 (Project CSD2006-0003), and the Fonds der Chemischen Industrie for financial support. E.G.P. was funded by ICM Grant P05-001.
Graphical Abstract
Adding 2Ns: Palladium catalysis introduces two nitrogen groups in a new regio and chemoselective diamination of non-activated alkenes that proceeds under entirely intermolecular reaction control. This palladium-catalyzed reaction employs commercial nitrogen sources in combination with a hypervalent iodo(III) reagent as oxidant (see scheme; Tos=toluenesulfonyl).
Supporting Information
Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors.
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