Helical Poly(quinoxaline-2,3-diyl)s Bearing Metal-Binding Sites as Polymer-Based Chiral Ligands for Asymmetric Catalysis†
Takeshi Yamamoto
Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510 (Japan), Fax: (+81) 75-383-2722 http://www.sbchem.kyoto-u.ac.jp/suginome-lab/
Search for more papers by this authorMichinori Suginome Prof. Dr.
Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510 (Japan), Fax: (+81) 75-383-2722 http://www.sbchem.kyoto-u.ac.jp/suginome-lab/
Search for more papers by this authorTakeshi Yamamoto
Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510 (Japan), Fax: (+81) 75-383-2722 http://www.sbchem.kyoto-u.ac.jp/suginome-lab/
Search for more papers by this authorMichinori Suginome Prof. Dr.
Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510 (Japan), Fax: (+81) 75-383-2722 http://www.sbchem.kyoto-u.ac.jp/suginome-lab/
Search for more papers by this authorThis work was supported by Grants-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science, and Technology (Japan) and the Ogasawara Foundation for the Promotion of Science and Engineering.
Graphical Abstract
Living it up: Helical polyquinoxalines with single and multiple metal-binding sites, prepared by living polymerization of o-diisocyanobenzenes, are used in the asymmetric hydrosilylation of styrenes, resulting in comparable enantioselectivities to those obtained by low-molecular-weight catalyst systems (up to 87 % ee, stereochemistry was determined by a chiral initiator) and a turnover number of almost 1000.
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