Self-Assembly of a Highly Stable, Topologically Interesting Metallamacrocycle by Bridging Gold(I) Ions with Pyridyl-2,6-diphenyl2− and Diphosphanes†
Steven C. F. Kui Dr.
Department of Chemistry and Open Laboratory of Chemical Biology, Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, P.R. China, Fax: (+852) 2857-1586
Search for more papers by this authorJie-Sheng Huang Dr.
Department of Chemistry and Open Laboratory of Chemical Biology, Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, P.R. China, Fax: (+852) 2857-1586
Search for more papers by this authorRaymond Wai-Yin Sun Dr.
Department of Chemistry and Open Laboratory of Chemical Biology, Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, P.R. China, Fax: (+852) 2857-1586
Search for more papers by this authorNianyong Zhu Dr.
Department of Chemistry and Open Laboratory of Chemical Biology, Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, P.R. China, Fax: (+852) 2857-1586
Search for more papers by this authorChi-Ming Che Prof. Dr.
Department of Chemistry and Open Laboratory of Chemical Biology, Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, P.R. China, Fax: (+852) 2857-1586
Search for more papers by this authorSteven C. F. Kui Dr.
Department of Chemistry and Open Laboratory of Chemical Biology, Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, P.R. China, Fax: (+852) 2857-1586
Search for more papers by this authorJie-Sheng Huang Dr.
Department of Chemistry and Open Laboratory of Chemical Biology, Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, P.R. China, Fax: (+852) 2857-1586
Search for more papers by this authorRaymond Wai-Yin Sun Dr.
Department of Chemistry and Open Laboratory of Chemical Biology, Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, P.R. China, Fax: (+852) 2857-1586
Search for more papers by this authorNianyong Zhu Dr.
Department of Chemistry and Open Laboratory of Chemical Biology, Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, P.R. China, Fax: (+852) 2857-1586
Search for more papers by this authorChi-Ming Che Prof. Dr.
Department of Chemistry and Open Laboratory of Chemical Biology, Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, P.R. China, Fax: (+852) 2857-1586
Search for more papers by this authorThis study was supported by The University of Hong Kong (University Development Fund), the Hong Kong Research Grants Council, and the University Grants Committee of the Hong Kong SAR of China (Area of Excellence Scheme, AoE/P-10/01).
Graphical Abstract
A Möbius arrangement of the bonds directly attached to a metallamacrocycle was observed for the AuI complex [Au3(CNC)(μ-Ph2PCH2PPh2)2]+, which was self-assembled by treating the lithium salt of pyridyl-2,6-diphenyl2− (CNC) with [Au2Cl2(μ-Ph2PCH2PPh2)]. The trinuclear AuI complex has intramolecular Au⋅⋅⋅Au and CH⋅⋅⋅π interactions, exhibits a remarkable stability in solution, and is cytotoxic toward cancer cell lines.
Supporting Information
Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2006/z600794_s.pdf or from the author.
Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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