Synthesis of the Mast Cell Degranulating (MCD) Peptide from Bee Venom^†

Corresponding Author

Priv.-Doz. Dr. Christian Birr

Max-Planck-Institut für Medizinische Forschung, Abteilung Naturstoff-Chemie, Jahnstrasse 29, D-6900 Heidelberg 1 (Germany)

Max-Planck-Institut für Medizinische Forschung, Abteilung Naturstoff-Chemie, Jahnstrasse 29, D-6900 Heidelberg 1 (Germany)Search for more papers by this author

Dr. Margot Wengert-Müller,

Dr. Margot Wengert-Müller

Max-Planck-Institut für Medizinische Forschung, Abteilung Naturstoff-Chemie, Jahnstrasse 29, D-6900 Heidelberg 1 (Germany)

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Priv.-Doz. Dr. Christian Birr,

Corresponding Author

Priv.-Doz. Dr. Christian Birr

Max-Planck-Institut für Medizinische Forschung, Abteilung Naturstoff-Chemie, Jahnstrasse 29, D-6900 Heidelberg 1 (Germany)

Max-Planck-Institut für Medizinische Forschung, Abteilung Naturstoff-Chemie, Jahnstrasse 29, D-6900 Heidelberg 1 (Germany)Search for more papers by this author

Dr. Margot Wengert-Müller,

Dr. Margot Wengert-Müller

Max-Planck-Institut für Medizinische Forschung, Abteilung Naturstoff-Chemie, Jahnstrasse 29, D-6900 Heidelberg 1 (Germany)

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First published: February 1979

https://doi.org/10.1002/anie.197901471

Citations: 6

^†

Ch. Birr, Lecture at German-Soviet Peptide Symposium, Eibsee 1978.—We are grateful to Prof. Dr. E. Habermann. Giessen, for a sample of MCD peptide.

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Abstract

Potential value in the therapy of rheumatism and other inflammation processes could attach to the MCD peptide from bee venom if it were available in larger quantities. The peptide consists of 22 amino acids and contains two disulfide bridges. Its first total synthesis has now been accomplished.

References

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Volume18, Issue2

February 1979

Pages 147-148

Synthesis of the Mast Cell Degranulating (MCD) Peptide from Bee Venom^†

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Synthesis of the Mast Cell Degranulating (MCD) Peptide from Bee Venom†

Abstract

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Synthesis of the Mast Cell Degranulating (MCD) Peptide from Bee Venom^†