Volume 129, Issue 10 p. 2558
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Innentitelbild: Anaerobe-Inspired Anticancer Nanovesicles (Angew. Chem. 10/2017)

Chenggen Qian

Chenggen Qian

Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC, 27695 USA

Center for Nanotechnology in Drug Delivery and Division of Pharmacoengineering Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599 USA

Department of Polymer Science and Engineering and Key Laboratory of High Performance Polymer Materials and Technology of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Jiangsu, Nanjing, 210023 P.R. China

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Peijian Feng

Peijian Feng

Department of Polymer Science and Engineering and Key Laboratory of High Performance Polymer Materials and Technology of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Jiangsu, Nanjing, 210023 P.R. China

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Jicheng Yu

Jicheng Yu

Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC, 27695 USA

Center for Nanotechnology in Drug Delivery and Division of Pharmacoengineering Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599 USA

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Dr. Yulei Chen

Dr. Yulei Chen

Department of Polymer Science and Engineering and Key Laboratory of High Performance Polymer Materials and Technology of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Jiangsu, Nanjing, 210023 P.R. China

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Quanyin Hu

Quanyin Hu

Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC, 27695 USA

Center for Nanotechnology in Drug Delivery and Division of Pharmacoengineering Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599 USA

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Wujin Sun

Wujin Sun

Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC, 27695 USA

Center for Nanotechnology in Drug Delivery and Division of Pharmacoengineering Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599 USA

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Xuanzhong Xiao

Xuanzhong Xiao

Department of Polymer Science and Engineering and Key Laboratory of High Performance Polymer Materials and Technology of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Jiangsu, Nanjing, 210023 P.R. China

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Dr. Xiuli Hu

Dr. Xiuli Hu

Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC, 27695 USA

Center for Nanotechnology in Drug Delivery and Division of Pharmacoengineering Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599 USA

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Adriano Bellotti

Adriano Bellotti

Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC, 27695 USA

Center for Nanotechnology in Drug Delivery and Division of Pharmacoengineering Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599 USA

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Prof. Dr. Qun-Dong Shen

Corresponding Author

Prof. Dr. Qun-Dong Shen

Department of Polymer Science and Engineering and Key Laboratory of High Performance Polymer Materials and Technology of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Jiangsu, Nanjing, 210023 P.R. China

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Prof. Dr. Zhen Gu

Corresponding Author

Prof. Dr. Zhen Gu

Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC, 27695 USA

Center for Nanotechnology in Drug Delivery and Division of Pharmacoengineering Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599 USA

Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, 27599 USA

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First published: 15 February 2017
Citations: 3

Graphical Abstract

Anaerobe Bakterien dienten als Vorlage für ein Wirkstofftransportsystem, das von Q. D. Shen, Z. Gu et al. in der Zuschrift auf S. 2632 ff. beschrieben wird. Die biomimetischen Nanovesikel sind in Zellen mit einer normalen physiologischen Redox- und Sauerstoffbilanz stabil. Bei Lichteinstrahlung brechen sie auf und entfalten ihre duale synergistische Antikrebswirkung mit erhöhter therapeutischer Wirkung.

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