Laser-Induced Cell Detachment and Patterning with Photodegradable Polymer Substrates†
Corresponding Author
Dr. George Pasparakis
Institute of Electronic Structure and Laser (IESL), Foundation for Research and Technology—Hellas (FORTH), P.O. Box 1527, 71110 Heraklion, Crete (Greece), Fax: (+30) 2810-391-305
Institute of Electronic Structure and Laser (IESL), Foundation for Research and Technology—Hellas (FORTH), P.O. Box 1527, 71110 Heraklion, Crete (Greece), Fax: (+30) 2810-391-305Search for more papers by this authorTheodore Manouras
Institute of Microelectronics, NCSR Demokritos, 15310 Aghia Paraskevi, Attiki (Greece)
Search for more papers by this authorDr. Alexandros Selimis
Institute of Electronic Structure and Laser (IESL), Foundation for Research and Technology—Hellas (FORTH), P.O. Box 1527, 71110 Heraklion, Crete (Greece), Fax: (+30) 2810-391-305
Search for more papers by this authorDr. Maria Vamvakaki
Institute of Electronic Structure and Laser (IESL), Foundation for Research and Technology—Hellas (FORTH), P.O. Box 1527, 71110 Heraklion, Crete (Greece), Fax: (+30) 2810-391-305
Department of Materials Science and Technology, University of Crete, 71003 Heraklion, Crete (Greece)
Search for more papers by this authorDr. Panagiotis Argitis
Institute of Microelectronics, NCSR Demokritos, 15310 Aghia Paraskevi, Attiki (Greece)
Search for more papers by this authorCorresponding Author
Dr. George Pasparakis
Institute of Electronic Structure and Laser (IESL), Foundation for Research and Technology—Hellas (FORTH), P.O. Box 1527, 71110 Heraklion, Crete (Greece), Fax: (+30) 2810-391-305
Institute of Electronic Structure and Laser (IESL), Foundation for Research and Technology—Hellas (FORTH), P.O. Box 1527, 71110 Heraklion, Crete (Greece), Fax: (+30) 2810-391-305Search for more papers by this authorTheodore Manouras
Institute of Microelectronics, NCSR Demokritos, 15310 Aghia Paraskevi, Attiki (Greece)
Search for more papers by this authorDr. Alexandros Selimis
Institute of Electronic Structure and Laser (IESL), Foundation for Research and Technology—Hellas (FORTH), P.O. Box 1527, 71110 Heraklion, Crete (Greece), Fax: (+30) 2810-391-305
Search for more papers by this authorDr. Maria Vamvakaki
Institute of Electronic Structure and Laser (IESL), Foundation for Research and Technology—Hellas (FORTH), P.O. Box 1527, 71110 Heraklion, Crete (Greece), Fax: (+30) 2810-391-305
Department of Materials Science and Technology, University of Crete, 71003 Heraklion, Crete (Greece)
Search for more papers by this authorDr. Panagiotis Argitis
Institute of Microelectronics, NCSR Demokritos, 15310 Aghia Paraskevi, Attiki (Greece)
Search for more papers by this authorWe gratefully acknowledge Thomas Papastathis for his help with the chamber design and Apostolos Englezis for his advice on the laser optics and setup.
Graphical Abstract
Schon durch Photolyse mit niedrigen Energien werden die Hauptketten von Polymeren gespalten, die zu effizienten Substraten für die sichere Abtrennung und Musterbildung von Zellen mithilfe von Laserlicht entwickelt wurden. Die Polymere, die neben Acetal- oder Ketaleinheiten auch absorbierende Gruppen im Rückgrat enthalten, zersetzen sich bei der Bestrahlung mit einem Excimer-Laser schnell, wodurch lebende Zellen freigesetzt werden konnten (siehe Bild).
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