Total Synthesis of Tryprostatins A and B†
Correction(s) for this article
-
Berichtigung: Total Synthesis of Tryprostatins A and B
- Volume 126Issue 34Angewandte Chemie
- pages: 8953-8953
- First Published online: August 13, 2014
Takayuki Yamakawa
Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan), Fax: (+81) 358-028-694
Search for more papers by this authorEiji Ideue
Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan), Fax: (+81) 358-028-694
Search for more papers by this authorJun Shimokawa
Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan), Fax: (+81) 358-028-694
Search for more papers by this authorCorresponding Author
Prof. Dr. Tohru Fukuyama
Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan), Fax: (+81) 358-028-694
Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan), Fax: (+81) 358-028-694Search for more papers by this authorTakayuki Yamakawa
Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan), Fax: (+81) 358-028-694
Search for more papers by this authorEiji Ideue
Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan), Fax: (+81) 358-028-694
Search for more papers by this authorJun Shimokawa
Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan), Fax: (+81) 358-028-694
Search for more papers by this authorCorresponding Author
Prof. Dr. Tohru Fukuyama
Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan), Fax: (+81) 358-028-694
Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan), Fax: (+81) 358-028-694Search for more papers by this authorFinancial support for this research was provided by Grants-in-Aid (21790009 and 20002004) from the Ministry of Education, Culture, Sports, Science and Technology of Japan.
Graphical Abstract
Gezähmte Radikale: Die Entwicklung verlässlicher Bedingungen für die radikalvermittelte Bildung von Indolen führte zur effizienten Synthese der Tryprostatine A und B. Mit dem Radikalstarter 2,2′-Azobis(4-methoxy-2,4-dimethylvaleronitril) gelang die radikalische Cyclisierung schon bei 30 °C, sodass die Bildung von Nebenprodukten unterdrückt war.
Supporting Information
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