A General Palladium-Catalyzed Suzuki–Miyaura Coupling of Aryl Mesylates†
Chau Ming So
Open Laboratory of Chirotechnology, The Institute of Molecular Technology for Drug Discovery and Synthesis, Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong (Hong Kong), Fax: (+852) 2364-9932
Search for more papers by this authorChak Po Lau Prof. Dr.
Open Laboratory of Chirotechnology, The Institute of Molecular Technology for Drug Discovery and Synthesis, Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong (Hong Kong), Fax: (+852) 2364-9932
Search for more papers by this authorFuk Yee Kwong Prof. Dr.
Open Laboratory of Chirotechnology, The Institute of Molecular Technology for Drug Discovery and Synthesis, Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong (Hong Kong), Fax: (+852) 2364-9932
Search for more papers by this authorChau Ming So
Open Laboratory of Chirotechnology, The Institute of Molecular Technology for Drug Discovery and Synthesis, Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong (Hong Kong), Fax: (+852) 2364-9932
Search for more papers by this authorChak Po Lau Prof. Dr.
Open Laboratory of Chirotechnology, The Institute of Molecular Technology for Drug Discovery and Synthesis, Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong (Hong Kong), Fax: (+852) 2364-9932
Search for more papers by this authorFuk Yee Kwong Prof. Dr.
Open Laboratory of Chirotechnology, The Institute of Molecular Technology for Drug Discovery and Synthesis, Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong (Hong Kong), Fax: (+852) 2364-9932
Search for more papers by this authorWe thank the Research Grants Council of Hong Kong (Project No. CERG: PolyU5008/06P) and University Grants Committee Areas of Excellence Scheme (Project No. AoE/P-10/01) for financial support.
Graphical Abstract
Katalysier das! Die hier vorgestellte erste palladiumkatalysierte Suzuki-Miyaura-Kupplung nicht aktivierter Arylmesylate gelingt nicht nur mit Arylboronsäuren, sondern auch mit anderen Organobor-Nucleophilen (Z=B(OH)2, BF3K, BPin), und die Reaktionsbedingungen sind mit einer Vielzahl gängiger funktioneller Gruppen (R1=Alkyl, OMe, CHO, CO, CN, CO2R′, Heteroaryl) kompatibel.
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