Iron-Catalyzed Alkylations of Aromatic Grignard Reagents†
Gérard Cahiez Prof.
Laboratoire de Synthèse Organique Sélective et de Chimie Organométallique (SOSCO), UMR 8123 CNRS-UCP-ESCOM, 5 Mail Gay-Lussac, Neuville s/Oise, 95092 Cergy-Pontoise, France, Fax: (+33) 1-3425-7383
Search for more papers by this authorVanessa Habiak
Laboratoire de Synthèse Organique Sélective et de Chimie Organométallique (SOSCO), UMR 8123 CNRS-UCP-ESCOM, 5 Mail Gay-Lussac, Neuville s/Oise, 95092 Cergy-Pontoise, France, Fax: (+33) 1-3425-7383
Search for more papers by this authorChristophe Duplais
Laboratoire de Synthèse Organique Sélective et de Chimie Organométallique (SOSCO), UMR 8123 CNRS-UCP-ESCOM, 5 Mail Gay-Lussac, Neuville s/Oise, 95092 Cergy-Pontoise, France, Fax: (+33) 1-3425-7383
Search for more papers by this authorAlban Moyeux
Laboratoire de Synthèse Organique Sélective et de Chimie Organométallique (SOSCO), UMR 8123 CNRS-UCP-ESCOM, 5 Mail Gay-Lussac, Neuville s/Oise, 95092 Cergy-Pontoise, France, Fax: (+33) 1-3425-7383
Search for more papers by this authorGérard Cahiez Prof.
Laboratoire de Synthèse Organique Sélective et de Chimie Organométallique (SOSCO), UMR 8123 CNRS-UCP-ESCOM, 5 Mail Gay-Lussac, Neuville s/Oise, 95092 Cergy-Pontoise, France, Fax: (+33) 1-3425-7383
Search for more papers by this authorVanessa Habiak
Laboratoire de Synthèse Organique Sélective et de Chimie Organométallique (SOSCO), UMR 8123 CNRS-UCP-ESCOM, 5 Mail Gay-Lussac, Neuville s/Oise, 95092 Cergy-Pontoise, France, Fax: (+33) 1-3425-7383
Search for more papers by this authorChristophe Duplais
Laboratoire de Synthèse Organique Sélective et de Chimie Organométallique (SOSCO), UMR 8123 CNRS-UCP-ESCOM, 5 Mail Gay-Lussac, Neuville s/Oise, 95092 Cergy-Pontoise, France, Fax: (+33) 1-3425-7383
Search for more papers by this authorAlban Moyeux
Laboratoire de Synthèse Organique Sélective et de Chimie Organométallique (SOSCO), UMR 8123 CNRS-UCP-ESCOM, 5 Mail Gay-Lussac, Neuville s/Oise, 95092 Cergy-Pontoise, France, Fax: (+33) 1-3425-7383
Search for more papers by this authorWe thank the CNRS and the Ecole Supérieure de Chimie Organique et Minérale (ESCOM) for their financial support as well as the Ministère de l'Education Nationale et de la Recherche for its financial support and a grant to A.M. The Fondation de France is acknowledged for a grant to C.D. and V.H.
Graphical Abstract
Nicht zum alten Eisen: Zwei effiziente eisenkatalysierte Kreuzkupplungen von Aryl-Grignard-Reagentien mit Alkylbromiden eignen sich für die Anwendung im großen Maßstab. Das erste Verfahren nutzt Eisenacetylacetonat und einen kooperativen Effekt der Liganden N,N,N′,N′-Tetramethylethylendiamin (TMEDA) und Hexamethylentetraamin (HMTA), im zweiten dient [(FeCl3)2(tmeda)3] als Katalysator.
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References
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