Propargylierung von Carbonylverbindungen durch Umpolung von Propargylpalladiumkomplexen mit Diethylzink
Corresponding Author
Prof. Yoshinao Tamaru
Department of Applied Chemistry, Faculty of Engineering Nagasaki University, 1–14 Bunnkyo, Nagasaki 852 (Japan) Telefax: Int. + 958/47–9008
Department of Applied Chemistry, Faculty of Engineering Nagasaki University, 1–14 Bunnkyo, Nagasaki 852 (Japan) Telefax: Int. + 958/47–9008Search for more papers by this authorSachio Goto
Department of Applied Chemistry, Faculty of Engineering Nagasaki University, 1–14 Bunnkyo, Nagasaki 852 (Japan) Telefax: Int. + 958/47–9008
Search for more papers by this authorAkihiro Tanaka
Department of Applied Chemistry, Faculty of Engineering Nagasaki University, 1–14 Bunnkyo, Nagasaki 852 (Japan) Telefax: Int. + 958/47–9008
Search for more papers by this authorMasamichi Shimizu
Department of Applied Chemistry, Faculty of Engineering Nagasaki University, 1–14 Bunnkyo, Nagasaki 852 (Japan) Telefax: Int. + 958/47–9008
Search for more papers by this authorDr. Masanari Kimura
Department of Applied Chemistry, Faculty of Engineering Nagasaki University, 1–14 Bunnkyo, Nagasaki 852 (Japan) Telefax: Int. + 958/47–9008
Search for more papers by this authorCorresponding Author
Prof. Yoshinao Tamaru
Department of Applied Chemistry, Faculty of Engineering Nagasaki University, 1–14 Bunnkyo, Nagasaki 852 (Japan) Telefax: Int. + 958/47–9008
Department of Applied Chemistry, Faculty of Engineering Nagasaki University, 1–14 Bunnkyo, Nagasaki 852 (Japan) Telefax: Int. + 958/47–9008Search for more papers by this authorSachio Goto
Department of Applied Chemistry, Faculty of Engineering Nagasaki University, 1–14 Bunnkyo, Nagasaki 852 (Japan) Telefax: Int. + 958/47–9008
Search for more papers by this authorAkihiro Tanaka
Department of Applied Chemistry, Faculty of Engineering Nagasaki University, 1–14 Bunnkyo, Nagasaki 852 (Japan) Telefax: Int. + 958/47–9008
Search for more papers by this authorMasamichi Shimizu
Department of Applied Chemistry, Faculty of Engineering Nagasaki University, 1–14 Bunnkyo, Nagasaki 852 (Japan) Telefax: Int. + 958/47–9008
Search for more papers by this authorDr. Masanari Kimura
Department of Applied Chemistry, Faculty of Engineering Nagasaki University, 1–14 Bunnkyo, Nagasaki 852 (Japan) Telefax: Int. + 958/47–9008
Search for more papers by this authorAbstract
Die ersten nucleophilen Additionen von Propargylpalladiumkomplexen gelangen mit den Umsetzungen (a), R1 = H, Me, Ph, R2 = H, Me, Ph, SiMe3. Dabei wurden nur im Fall R1 = H, R2 = Me, Ph neben dem Homopropargylalkohol 1 auch der Allenylalkohol 2 und im Fall R1 = Ph, R2 = H das Ethylallen 3 gebildet.
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- 6 Ketone scheinen ähnlich gut zu reagieren. So ergab die Reaktion von 1 b (X = OBz) mit Acetophenon unter den in Eintrag 2 von Tabelle 1 genannten Bedingungen (THF, 29 h) 3-Methyl-2-phenyl-4-pentin-2-ol in 58% Ausbeute.
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