Brief Communication

Vestibulo-ocular reflex pathways in internuclear ophthalmoplegia

Corresponding Author

Phillip D. Cremer FRACP

Eye and Ear Research Unit, Royal Prince Alfred Hospital University of Sydney, Sydney, Australia

Department of Neurology, Royal Prince Alfred Hospital, Missenden Road, Camperdown, New South Wales 2050, AustraliaSearch for more papers by this author

Americo A. Migliaccio M Biomed Eng,

Americo A. Migliaccio M Biomed Eng

Eye and Ear Research Unit, Royal Prince Alfred Hospital University of Sydney, Sydney, Australia

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G. Michael Halmagyi MD,

G. Michael Halmagyi MD

Eye and Ear Research Unit, Royal Prince Alfred Hospital University of Sydney, Sydney, Australia

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Ian S. Curthoys PhD,

Ian S. Curthoys PhD

Eye and Ear Research Unit, Royal Prince Alfred Hospital University of Sydney, Sydney, Australia

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Phillip D. Cremer FRACP,

Corresponding Author

Phillip D. Cremer FRACP

Eye and Ear Research Unit, Royal Prince Alfred Hospital University of Sydney, Sydney, Australia

Department of Neurology, Royal Prince Alfred Hospital, Missenden Road, Camperdown, New South Wales 2050, AustraliaSearch for more papers by this author

Americo A. Migliaccio M Biomed Eng,

Americo A. Migliaccio M Biomed Eng

Eye and Ear Research Unit, Royal Prince Alfred Hospital University of Sydney, Sydney, Australia

Search for more papers by this author

G. Michael Halmagyi MD,

G. Michael Halmagyi MD

Eye and Ear Research Unit, Royal Prince Alfred Hospital University of Sydney, Sydney, Australia

Search for more papers by this author

Ian S. Curthoys PhD,

Ian S. Curthoys PhD

Eye and Ear Research Unit, Royal Prince Alfred Hospital University of Sydney, Sydney, Australia

Search for more papers by this author

First published: 31 May 2001

https://doi.org/10.1002/1531-8249(199904)45:4<529::AID-ANA18>3.0.CO;2-H

Citations: 47

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Abstract

We measured the vestibulo-ocular reflex (VOR) during head impulses in a patient with right-sided internuclear ophthalmoplegia. Head impulses are rapid, passive, high-acceleration, low-amplitude head rotations in the direction of a particular semicircular canal (SCC). Adduction of the right eye was abnormally slow during right lateral SCC head impulses. The VOR during left posterior SCC impulses was severely deficient in both eyes, but the VOR during left anterior SCC impulses was only slightly deficient. We suggest that the vertical vestibulo-ocular pathways in humans are connected in SCC-plane coordinates, not the traditional roll and pitch coordinates, and that anterior SCC signals do not travel exclusively in the medial longitudinal fasciculus. Ann Neurol 1999;45:529–533

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Volume45, Issue4

April 1999

Pages 529-533

Vestibulo-ocular reflex pathways in internuclear ophthalmoplegia

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Vestibulo-ocular reflex pathways in internuclear ophthalmoplegia

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