Rhenium(VII) Oxo Complexes as Extremely Active Catalysts in the Dehydration of Primary Amides and Aldoximes to Nitriles
Kazuaki Ishihara Prof. Dr.
Graduate School of Engineering, Nagoya University SORST, Japan and Science Technology Corporation (JST) Furo-cho, Chikusa, Nagoya 464-8603 (Japan) Fax: (+81) 52-789-3222
Search for more papers by this authorYoshiro Furuya
Graduate School of Engineering, Nagoya University SORST, Japan and Science Technology Corporation (JST) Furo-cho, Chikusa, Nagoya 464-8603 (Japan) Fax: (+81) 52-789-3222
Search for more papers by this authorHisashi Yamamoto Prof. Dr.
Graduate School of Engineering, Nagoya University SORST, Japan and Science Technology Corporation (JST) Furo-cho, Chikusa, Nagoya 464-8603 (Japan) Fax: (+81) 52-789-3222
Search for more papers by this authorKazuaki Ishihara Prof. Dr.
Graduate School of Engineering, Nagoya University SORST, Japan and Science Technology Corporation (JST) Furo-cho, Chikusa, Nagoya 464-8603 (Japan) Fax: (+81) 52-789-3222
Search for more papers by this authorYoshiro Furuya
Graduate School of Engineering, Nagoya University SORST, Japan and Science Technology Corporation (JST) Furo-cho, Chikusa, Nagoya 464-8603 (Japan) Fax: (+81) 52-789-3222
Search for more papers by this authorHisashi Yamamoto Prof. Dr.
Graduate School of Engineering, Nagoya University SORST, Japan and Science Technology Corporation (JST) Furo-cho, Chikusa, Nagoya 464-8603 (Japan) Fax: (+81) 52-789-3222
Search for more papers by this authorGraphical Abstract
An economical and environmentally benign process for the preparation of nitriles by the dehydration of primary amides and aldoximes is catalyzed by rhenium(VII) oxo complexes such as perrhenic acid and trimethylsilylperrhenate (see scheme). The reaction proceeds at azeotropic reflux (with the removal of water) under essentially neutral conditions.
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