REVIEW
Mulberry plant as a source of functional food with therapeutic and nutritional applications: A review
Maria Maqsood,
Raakia Anam Saeed,
Amna Sahar,
Muhammad Issa Khan,
Maria Maqsood
National Institute of Food Science and Technology, University of Agriculture, Faisalabad, Pakistan
Contribution: Conceptualization, Visualization, Writing - original draft, Writing - review & editing
Search for more papers by this authorRaakia Anam Saeed
National Institute of Food Science and Technology, University of Agriculture, Faisalabad, Pakistan
Contribution: Writing - review & editing
Search for more papers by this authorAmna Sahar
Department of Food Engineering, University of Agriculture, Faisalabad, Pakistan
Contribution: Writing - review & editing
Search for more papers by this authorCorresponding Author
Muhammad Issa Khan
National Institute of Food Science and Technology, University of Agriculture, Faisalabad, Pakistan
Correspondence
Muhammad Issa Khan, National Institute of Food Science and Technology, University of Agriculture, Faisalabad 38000, Pakistan.
Email: [email protected]
Contribution: Supervision, Writing - review & editing
Search for more papers by this authorMaria Maqsood,
Raakia Anam Saeed,
Amna Sahar,
Muhammad Issa Khan,
Maria Maqsood
National Institute of Food Science and Technology, University of Agriculture, Faisalabad, Pakistan
Contribution: Conceptualization, Visualization, Writing - original draft, Writing - review & editing
Search for more papers by this authorRaakia Anam Saeed
National Institute of Food Science and Technology, University of Agriculture, Faisalabad, Pakistan
Contribution: Writing - review & editing
Search for more papers by this authorAmna Sahar
Department of Food Engineering, University of Agriculture, Faisalabad, Pakistan
Contribution: Writing - review & editing
Search for more papers by this authorCorresponding Author
Muhammad Issa Khan
National Institute of Food Science and Technology, University of Agriculture, Faisalabad, Pakistan
Correspondence
Muhammad Issa Khan, National Institute of Food Science and Technology, University of Agriculture, Faisalabad 38000, Pakistan.
Email: [email protected]
Contribution: Supervision, Writing - review & editing
Search for more papers by this authorAbstract
Medicinal plants from the family Moraceae have diverse applications in agriculture, cosmetics, food, and the pharmaceutical industry. Their extensive spectrum of pharmacological activity for treating numerous inflammatory illnesses, cancer, cardiovascular diseases, and gastrointestinal problems reflects their biological and therapeutic value. This article summarizes the molecular mechanisms related to the biological implications of mulberry extracts, fractions, and isolated bioactive compounds from different parts in various health-related ailments. Additionally, the food industry and animal nutrition applications are summarized. Phytochemicals such as steroids, saponins, alkaloids, glycosides, polysaccharides, and phenolic compounds including terpenoids, flavonoids, anthocyanins, and tannins are found in this medicinal plant. The aqueous, ethanolic, and methanolic extracts, as well as bioactive compounds, have anti-oxidative, hypoglycemic, nephroprotective, antimicrobial, neuroprotective, anti-mutagenic, hepatoprotective, anthelmintic, immune-modulatory, cardioprotective, and skin protecting activities. Mulberry supplementation in food products improves the stability of phenolics, sensory properties, antioxidant activity, and antimicrobial properties. Mulberry leaves in animal feed increase the nutrient digestibility, growth parameters, antimicrobial, and antioxidant properties.
Practical applications
This review summarized the in vivo and in vitro biological activities of the mulberry and isolated constituents in various health conditions. In addition, the food uses such as antioxidant potential, antimicrobial, and physicochemical properties were discussed. Furthermore, in vivo studies revealed mulberry as a significant protein source and its flavonoids as potential animal foliage.
CONFLICT OF INTEREST
The authors declare no conflict of interest.
Open Research
DATA AVAILABILITY STATEMENT
Data sharing not applicable.
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