Cinnamon, an effective anti-obesity agent: Evidence from an umbrella meta-analysis
Majid Keramati
Student Research Committee, Nutrition Research Center, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
Contribution: Data curation, Investigation, Writing - original draft
Search for more papers by this authorVali Musazadeh
Student Research Committee, Nutrition Research Center, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
Contribution: Data curation, Investigation, Writing - original draft
Search for more papers by this authorMahsa Malekahmadi
Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation, Investigation, Writing - original draft
Search for more papers by this authorParmida Jamilian
School of Pharmacy and Bio Engineering, Keele University, Keele, UK
Contribution: Writing - review & editing
Search for more papers by this authorParsa Jamilian
Keele University School of Medicine, Keele University, Keele, UK
Contribution: Writing - review & editing
Search for more papers by this authorZohre Ghoreishi
Department of Clinical Nutrition, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran
Contribution: Investigation, Supervision, Validation, Writing - review & editing
Search for more papers by this authorCorresponding Author
Meysam Zarezadeh
Student Research Committee, Nutrition Research Center, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
Nutrition Research Center, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
Correspondence
Meysam Zarezadeh, Faculty of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Attar-Neishaburi St., Golgasht Alley, Azadi Blvd., Tabriz, Iran.
Email: [email protected]
Alireza Ostadrahimi, Nutrition Research Center, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Attar-Neishaburi St. Golgasht Alley, Azadi Blvd., Tabriz, Iran.
Email: [email protected]
Contribution: Conceptualization, Formal analysis, Methodology, Supervision, Writing - review & editing
Search for more papers by this authorCorresponding Author
Alireza Ostadrahimi
Nutrition Research Center, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
Correspondence
Meysam Zarezadeh, Faculty of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Attar-Neishaburi St., Golgasht Alley, Azadi Blvd., Tabriz, Iran.
Email: [email protected]
Alireza Ostadrahimi, Nutrition Research Center, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Attar-Neishaburi St. Golgasht Alley, Azadi Blvd., Tabriz, Iran.
Email: [email protected]
Contribution: Supervision, Writing - review & editing
Search for more papers by this authorMajid Keramati
Student Research Committee, Nutrition Research Center, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
Contribution: Data curation, Investigation, Writing - original draft
Search for more papers by this authorVali Musazadeh
Student Research Committee, Nutrition Research Center, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
Contribution: Data curation, Investigation, Writing - original draft
Search for more papers by this authorMahsa Malekahmadi
Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
Contribution: Data curation, Investigation, Writing - original draft
Search for more papers by this authorParmida Jamilian
School of Pharmacy and Bio Engineering, Keele University, Keele, UK
Contribution: Writing - review & editing
Search for more papers by this authorParsa Jamilian
Keele University School of Medicine, Keele University, Keele, UK
Contribution: Writing - review & editing
Search for more papers by this authorZohre Ghoreishi
Department of Clinical Nutrition, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran
Contribution: Investigation, Supervision, Validation, Writing - review & editing
Search for more papers by this authorCorresponding Author
Meysam Zarezadeh
Student Research Committee, Nutrition Research Center, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
Nutrition Research Center, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
Correspondence
Meysam Zarezadeh, Faculty of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Attar-Neishaburi St., Golgasht Alley, Azadi Blvd., Tabriz, Iran.
Email: [email protected]
Alireza Ostadrahimi, Nutrition Research Center, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Attar-Neishaburi St. Golgasht Alley, Azadi Blvd., Tabriz, Iran.
Email: [email protected]
Contribution: Conceptualization, Formal analysis, Methodology, Supervision, Writing - review & editing
Search for more papers by this authorCorresponding Author
Alireza Ostadrahimi
Nutrition Research Center, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
Correspondence
Meysam Zarezadeh, Faculty of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Attar-Neishaburi St., Golgasht Alley, Azadi Blvd., Tabriz, Iran.
Email: [email protected]
Alireza Ostadrahimi, Nutrition Research Center, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Attar-Neishaburi St. Golgasht Alley, Azadi Blvd., Tabriz, Iran.
Email: [email protected]
Contribution: Supervision, Writing - review & editing
Search for more papers by this authorMajid Keramati and Vali Musazadeh have contributed equally to this work and share first authorship.
Abstract
The evidence provided by meta-analyses on the beneficial impacts of cinnamon supplementation on anthropometric indices are still conflicting. Present study’s aim was to evaluate the effects of cinnamon on obesity indices by an umbrella meta-analysis. The electronic databases including Web of Science, PubMed, EMBASE, Scopus were systematically searched up to March 2021. Data for the effects of cinnamon on anthropometric indices were collected from the meta-analyses. An umbrella meta-analysis was carried out using a random-effects model. The pooled effects of 7 meta-analyses showed that cinnamon supplementation significantly reduced body weight (ES: −0.67 kg; 95% CI: −0.99, −0.35, p ˂ .001), body mass index (ES: −0.45 kg/m2; 95% CI: −0.57, −0.33, p ˂ .001) in comparison to control group. However, the effects of cinnamon on waist circumference (ES: −1.05 cm; 95% CI: −2.26, 0.15, p = .087) were not considerable. According to results, cinnamon could be suggested as a complementary weight loss agent. Favorable results were obtained at a dose of ≥3 g/day. In this study, a comprehensive study was performed on meta-analyses performed on the effect of cinnamon on anthropometric indices. This study could be considered as a final conclusion about the effect of cinnamon on anthropometric indices. The results of this study showed that supplementation with cinnamon significantly reduces BMI and body weight. The impacts were greater in doses of ≥3 g/day and in PCOS patients.
Practical applications
In this study, a comprehensive study was performed on meta-analyses performed on the effect of cinnamon on anthropometric indices. This study could be considered as a final conclusion about the effect of cinnamon on anthropometric indices. The results of this study showed that supplementation with cinnamon significantly reduces BMI and body weight. The impacts were greater in doses of ≥3 g/day and in PCOS patients.
CONFLICTS OF INTEREST
There were no personal or financial conflicts of interest stated by the authors.
Open Research
DATA AVAILABILITY STATEMENT
All the materials used in this systematic review and meta-analysis have been fully referenced.
Supporting Information
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Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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