Volume 46, Issue 11 e14150
ORIGINAL ARTICLE

Functional cereals' anti-diabetic property, phenolic composition, and role on glycemic indices in-vitro

Ayokunle Olubode Ademosun

Corresponding Author

Ayokunle Olubode Ademosun

Department of Biochemistry, Federal University of Technology, Akure, Nigeria

Correspondence

Ayokunle Olubode Ademosun, Department of Biochemistry, Federal University of Technology, P.M.B. 704, Akure 340001, Nigeria.

Email: [email protected]

Contribution: Conceptualization, Data curation, Formal analysis, ​Investigation, Methodology, Resources, Supervision, Visualization, Writing - review & editing

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Aanuoluwa Ruth Olaniyan

Aanuoluwa Ruth Olaniyan

Department of Biochemistry, Federal University of Technology, Akure, Nigeria

Contribution: Data curation, Formal analysis, Funding acquisition, ​Investigation, Methodology, Resources, Writing - review & editing

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Olufunke Florence Ajeigbe

Olufunke Florence Ajeigbe

Department of Biochemistry, Federal University of Technology, Akure, Nigeria

Department of Physical and Chemical Sciences, Biochemistry Programme, Elizade University, Ilara-Mokin, Nigeria

Contribution: Conceptualization, Methodology, Resources, Supervision, Validation, Visualization, Writing - original draft, Writing - review & editing

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Ganiyu Oboh

Ganiyu Oboh

Department of Biochemistry, Federal University of Technology, Akure, Nigeria

Contribution: Conceptualization, Data curation, Funding acquisition, Resources, Supervision, Visualization, Writing - review & editing

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First published: 25 March 2022
Citations: 2

Abstract

This study analyzed the effects of functional cereals processed and produced from yellow corn, soybean, acha, orange peels and moringa leaves' polyphenolic content, glycemic index, starch composition and their effects on α-amylase and α-glucosidase enzymes in vitro. Functional cereals were produced as ready-to-eat cereals at different proportion with variations in the amount of measured acha flour, soybean flour, and blends of orange peels and moringa leaves while maintaining a constant amount of yellow corn. The produced orange peels and moringa leaves blends inclusion to functional cereals had significantly increased phenolic constituents, showed inhibitory activity on α-amylase and α-glucosidase enzymes in-vitro and reduced glycemic index, starch content and starch to sugar ratios. Interestingly, amongst the produced functional cereals, the best two cereals were with their composition made up of corn, acha, soybean, orange peel, moringa leaves (30: 5:15: 0.5: 0.5) and corn, acha, soybean, moringa leaves (30: 5: 15: 1) which both had the high inhibitory effects on the activities of α-amylase and α-glucosidase while depleting starch content in-vitro when compared with commercially consumed cereals (golden morn).

Practical applications

Ready-to-eat cereals are highly consumed by children and by adults inclusively. Commercial breakfast cereals are readily available and consumed irrespective of the fact it has high calorie constituent as more emphasis is placed on their nutrients value which includes vitamins A, vitamin C and calcium for boosting immune system and for proper body growth and functioning. However, these commercial breakfast cereals (golden morn) owing to the high maize and millet content present in them are unfavorable to certain consumers or individuals with health challenges such as diabetic patients. This study shows that functional cereals produced in-vitro extensively are not only nutritious but also medicinal in nature, offering benefits in the management of diabetes and related complications.

CONFLICT OF INTEREST

The authors declare no conflict of interest.

DATA AVAILABILITY STATEMENT

The data that support the findings of this study are made available by contacting the corresponding author ([email protected])

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