A rare case of multinodular pulmonary amyloidosis
Authorship and contributorship:
Jizhen Feng and Qingwei Liu are responsible for initiating and performing the study. Jiamei Li and Chunxiang Ling have made substantial contribution in developing the case record form and interpreting the data.
Ethics:
Approval of the concerned ethics committee was given and written informed consent was given by the studied patient.
Conflict of interest:
The authors have stated explicitly that there are no conflicts of interest in connection with this article.
Abstract
Background and Aims
Pulmonary amyloidosis is usually associated with systemic amyloidosis. Localized pulmonary amyloidosis without systemic amyloidosis is even rare. We reported a rare case of multinodular pulmonary amyloidosis to improve the understanding of the disease.
Methods
Report of a case.
Results
We present an unusual case of primary pulmonary multinodular amyloidosis in a middle-aged woman. She presented our hospital with cough and chest distress only. Results of computed tomography (CT) showed multiple nodules with diffused calcification and thick-walled cavity in bilateral lung parenchyma. And the diagnosis of nodular amyloidosis was established by a CT-guided core needle biopsy.
Conclusions
The case clearly shows it is difficult to distinguish parenchymal nodular amyloidosis from malignant primary lung neoplasm in radiology because of their similar images. Thus, the role of CT-guided core needle biopsy in diagnosis of pulmonary mutinodular amyloidosis is very important.