Volume 7, Issue 4 pp. 465-472

Original Article

Changing relative contribution of abdominal obesity and a family history of diabetes on prevalence of diabetes mellitus in Korean men and women aged 30–49 years from 2001 to 2010 从2001至2010年在韩国30–49岁年龄段的男性与女性中腹型肥胖以及糖尿病家族史对糖尿病患病率相对贡献度的变化

Bo Kyung Koo,

Bo Kyung Koo

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea

Department of Internal Medicine, Boramae Medical Center, Seoul, Korea

Search for more papers by this author

Sang Wan Kim,

Sang Wan Kim

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea

Department of Internal Medicine, Boramae Medical Center, Seoul, Korea

Search for more papers by this author

Ka Hee Yi,

Ka Hee Yi

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea

Department of Internal Medicine, Boramae Medical Center, Seoul, Korea

Search for more papers by this author

Kyong Soo Park,

Kyong Soo Park

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea

Search for more papers by this author

Min Kyong Moon,

Corresponding Author

Min Kyong Moon

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea

Department of Internal Medicine, Boramae Medical Center, Seoul, Korea

Correspondence

Min Kyong Moon, Department of Internal Medicine, Seoul National University College of Medicine, 39 Boramae Road, Dongjak-Gu, Seoul 156-707, Korea.

Tel: +82 2870 2226

Fax: +82 2831 2826

Email: [email protected]

Search for more papers by this author

Bo Kyung Koo,

Bo Kyung Koo

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea

Department of Internal Medicine, Boramae Medical Center, Seoul, Korea

Search for more papers by this author

Sang Wan Kim,

Sang Wan Kim

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea

Department of Internal Medicine, Boramae Medical Center, Seoul, Korea

Search for more papers by this author

Ka Hee Yi,

Ka Hee Yi

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea

Department of Internal Medicine, Boramae Medical Center, Seoul, Korea

Search for more papers by this author

Kyong Soo Park,

Kyong Soo Park

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea

Search for more papers by this author

Min Kyong Moon,

Corresponding Author

Min Kyong Moon

Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea

Department of Internal Medicine, Boramae Medical Center, Seoul, Korea

Correspondence

Min Kyong Moon, Department of Internal Medicine, Seoul National University College of Medicine, 39 Boramae Road, Dongjak-Gu, Seoul 156-707, Korea.

Tel: +82 2870 2226

Fax: +82 2831 2826

Email: [email protected]

Search for more papers by this author

First published: 21 July 2014

https://doi.org/10.1111/1753-0407.12202

Citations: 12

Share a link

Email
Wechat
Bluesky

Abstract

Background

We investigated the change in the relative impact of a family history of diabetes (FH) and abdominal obesity on diabetes mellitus (DM) over a 10-year period in Korea.

Methods

We analyzed data from the 2001, 2005, and 2010 Korean National Health and Nutrition Examination Survey that were weighted to represent the entire Korean population in each year. Multiple logistic regression analysis was used to examine the association between DM and FH or abdominal obesity.

Results

In men aged 30–49 years, the association between FH and DM was stronger in 2010 than in 2001; the odds ratio (OR) was 1.508 (95% confidence interval [CI], 0.814–2.792) in 2001, 3.351 (95% CI, 1.599–7.024) in 2005, and 7.302 (95% CI, 3.451–15.451) in 2010 (P for trend = 0.003). In contrast, the association between abdominal obesity and DM was weaker in 2010 (OR, 0.969 [95% CI, 0.465–2.018]) than in 2001 (OR, 2.532 [95% CI, 1.572–4.080]) (P for trend = 0.037). In women aged 30–49 years, there was no significant change in OR of FH or abdominal obesity during the same period. (P for trend = 0.367 and 0.401, respectively).

Conclusions

In Korean men aged 30–49 years, the association between FH and DM has been stronger from 2001 to 2010, whereas abdominal obesity was less important in 2010 compared to 2001.

摘要

背景：

我们在韩国调查了糖尿病家族史以及腹型肥胖对糖尿病（DM）的相对影响在10年期间的变化情况。

方法：

我们对2001、2005以及2010年韩国全国健康与营养调查研究的数据进行了分析，这些数据加权后代表了韩国每年人口的整体情况。使用多元logistic回归分析来调查DM与糖尿病家族史或腹型肥胖之间的关系。

结果：

在30–49岁的男性中，2010年糖尿病家族史与DM之间的关系比2001年更紧密；2001年的优势比（OR）为1.508（95% CI，0.814–2.792），2005年为3.351（95% CI，1.599–7.024），2010年为7.302（95% CI，3.451–15.451）（趋势的P值为0.003）。相反，2010年腹型肥胖与DM之间的关系（OR，0.969[95% CI，0.465–2.018]）却比2001年（OR，2.532[95% CI，1.572–4.080]）更弱（趋势的P值为0.037）。在30–49岁的女性中，同一时期内的糖尿病家族史或腹型肥胖的OR值都没有显著性的变化（趋势的P值分别为0.367与0.401）

结论：

在30–49岁的韩国男性中，从2001至2010年糖尿病家族史与DM之间的相关性变得更强了，然而与2001年相比，2010年的腹型肥胖却变得不那么重要了。

Supporting Information

References

1Ng MC, Park KS, Oh B et al. Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians. Diabetes. 2008; 57: 2226–2233.
10.2337/db07-1583
CAS PubMed Web of Science® Google Scholar
2Voight BF, Scott LJ, Steinthorsdottir V et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet. 2010; 42: 579–589.
10.1038/ng.609
CAS PubMed Web of Science® Google Scholar
3Zeggini E, Scott LJ, Saxena R et al. Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet. 2008; 40: 638–645.
10.1038/ng.120
CAS PubMed Web of Science® Google Scholar
4Vassy JL, Durant NH, Kabagambe EK et al. A genotype risk score predicts type 2 diabetes from young adulthood: The CARDIA study. Diabetologia. 2012; 55: 2604–2612.
10.1007/s00125-012-2637-7
CAS PubMed Web of Science® Google Scholar
5Meigs JB, Shrader P, Sullivan LM et al. Genotype score in addition to common risk factors for prediction of type 2 diabetes. N Engl J Med. 2008; 359: 2208–2219.
10.1056/NEJMoa0804742
CAS PubMed Web of Science® Google Scholar
6de Miguel-Yanes JM, Shrader P, Pencina MJ et al. Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms. Diabetes Care. 2011; 34: 121–125.
10.2337/dc10-1265
PubMed Web of Science® Google Scholar
7Kim DJ. The epidemiology of diabetes in Korea. Diabetes Metab. 2011; 35: 303–308.
10.4093/dmj.2011.35.4.303
Google Scholar
8Choi YJ, Kim HC, Kim HM, Park SW, Kim J, Kim DJ. Prevalence and management of diabetes in Korean adults: Korea National Health and Nutrition Examination Surveys 1998–2005. Diabetes Care. 2009; 32: 2016–2020.
10.2337/dc08-2228
PubMed Web of Science® Google Scholar
9Koo BK, Kim EK, Choi H, Park KS, Moon MK. Decreasing trends of the prevalence of diabetes and obesity in korean women aged 30-59 years over the past decade: Results from the korean national health and nutrition examination survey, 2001–2010. Diabetes Care. 2013; 36: e95–96.
10.2337/dc13-0247
PubMed Web of Science® Google Scholar
10Rhee SY, Park SW, Kim DJ, Woo J. Gender disparity in the secular trends for obesity prevalence in Korea: Analyses based on the KNHANES 1998-2009. Korean J Intern Med. 2013; 28: 29–34.
10.3904/kjim.2013.28.1.29
PubMed Web of Science® Google Scholar
11Lim S, Shin H, Song JH et al. Increasing prevalence of metabolic syndrome in Korea: The Korean National Health and Nutrition Examination Survey for 1998–2007. Diabetes Care. 2011; 34: 1323–1328.
10.2337/dc10-2109
CAS PubMed Web of Science® Google Scholar
12Lee WK, Kong KA, Park H. Effect of preexisting musculoskeletal diseases on the 1-year incidence of fall-related injuries. J Prev Med Public Health. 2012; 45: 283–290.
10.3961/jpmph.2012.45.5.283
PubMed Web of Science® Google Scholar
13Toth MJ, Tchernof A, Sites CK, Poehlman ET. Menopause-related changes in body fat distribution. Ann N Y Acad Sci. 2000; 904: 502–506.
10.1111/j.1749-6632.2000.tb06506.x
CAS PubMed Web of Science® Google Scholar
14Poehlman ET, Toth MJ, Gardner AW. Changes in energy balance and body composition at menopause: A controlled longitudinal study. Ann Intern Med. 1995; 123: 673–675.
10.7326/0003-4819-123-9-199511010-00005
PubMed Web of Science® Google Scholar
15Eshtiaghi R, Esteghamati A, Nakhjavani M. Menopause is an independent predictor of metabolic syndrome in Iranian women. Maturitas. 2010; 65: 262–266.
10.1016/j.maturitas.2009.11.004
PubMed Web of Science® Google Scholar
16 World Health Organisation IAftSoO, International Obesity TaskForce. The Asia-Pacific Perspective: Redefining Obesity and its Treatment. Health Communications; 2000; Sydney.
Google Scholar
17Grundy SM, Cleeman JI, Daniels SR et al. Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation. 2005; 112: 2735–2752.
10.1161/CIRCULATIONAHA.105.169404
PubMed Web of Science® Google Scholar
18Hu FB, Manson JE, Stampfer MJ et al. Diet, lifestyle, and the risk of type 2 diabetes mellitus in women. N Engl J Med. 2001; 345: 790–797.
10.1056/NEJMoa010492
CAS PubMed Web of Science® Google Scholar
19Cho YM, Kim TH, Lim S et al. Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population. Diabetologia. 2009; 52: 253–261.
10.1007/s00125-008-1196-4
CAS PubMed Web of Science® Google Scholar
20Zhang C, Qi L, Hunter DJ et al. Variant of transcription factor 7-like 2 (TCF7L2) gene and the risk of type 2 diabetes in large cohorts of U.S. women and men. Diabetes. 2006; 55: 2645–2648.
10.2337/db06-0643
CAS PubMed Web of Science® Google Scholar
21 American Diabetes A. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2014; 37 (Suppl 1): S81–90.
10.2337/dc14-S081
PubMed Web of Science® Google Scholar
22Valdez R, Yoon PW, Liu T, Khoury MJ. Family history and prevalence of diabetes in the U.S. population: The 6-year results from the National Health and Nutrition Examination Survey (1999-2004). Diabetes Care. 2007; 30: 2517–2522.
10.2337/dc07-0720
PubMed Web of Science® Google Scholar
23 American Diabetes A. Preconception care of women with diabetes. Diabetes Care. 2004; 27 (Suppl 1): S76–78.
PubMed Google Scholar
24Brody SC, Harris R, Lohr K. Screening for gestational diabetes: A summary of the evidence for the U.S. Preventive Services Task Force. Obstet Gynecol. 2003; 101: 380–392.
10.1097/00006250-200302000-00027
PubMed Web of Science® Google Scholar
25Metzger BE. Long-term outcomes in mothers diagnosed with gestational diabetes mellitus and their offspring. Clin Obstet Gynecol. 2007; 50: 972–979.
10.1097/GRF.0b013e31815a61d6
PubMed Web of Science® Google Scholar
26Cho NH, Jang HC, Park HK, Cho YW. Waist circumference is the key risk factor for diabetes in Korean women with history of gestational diabetes. Diabetes Res Clin Pract. 2006; 71: 177–183.
10.1016/j.diabres.2005.06.003
PubMed Web of Science® Google Scholar
27Jang HC. Gestational diabetes in Korea: Incidence and risk factors of diabetes in women with previous gestational diabetes. Diabetes Metab J. 2011; 35: 1–7.
10.4093/dmj.2011.35.1.1
PubMed Google Scholar

Citing Literature

Volume7, Issue4

July 2015

Pages 465-472

Abstract

Background

Methods

Results

Conclusions

摘要

背景：

方法：

结果：

结论：

Supporting Information

References

Citing Literature

References

Information

About Wiley Online Library

Help & Support

Opportunities

Connect with Wiley

Abstract

Background

Methods

Results

Conclusions

摘要

背景：

方法：

结果：

结论：

Supporting Information

References

Citing Literature

References

Related

Information