Anhydrides, imides, N-ethylimides, N-hydroxyimides and N-aminoimides of 1,4,5,6-tetramethyl-bicyclo[5.2.1.0^2,6]hept-5-ene-2,3-dicarboxylic acid, 1,4,5,6,7-pentamethyl-bicyclo[5.2.1.0^2,6]hept-5-ene-2,3-dicarboxylic acid and 7-ethyl-1,4,5,6-tetramethyl-bicyclo[5.2.1.0^2,6]hept-5-ene-2,3-dicarboxylic acid were obtained. Antimicrobial activity of the newly obtained derivatives was tested against selected Gram-positive and Gram-negative bacteria and fungi of the Candida species. The structures of obtained compounds and their antimicrobial activity were compared. Structure of 1b, 2b and 1e were determined by an X-ray analysis.

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Volume55, Issue6

December 2008

Pages 1258-1265

Synthesis and Structural Characterisation of Derivatives of Tricyclo[5.2.1.0^2,6]Dec-8-Ene-3,5-Dione with an Expected Antimicrobial Activity

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Synthesis and Structural Characterisation of Derivatives of Tricyclo[5.2.1.02,6]Dec-8-Ene-3,5-Dione with an Expected Antimicrobial Activity

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Synthesis and Structural Characterisation of Derivatives of Tricyclo[5.2.1.0^2,6]Dec-8-Ene-3,5-Dione with an Expected Antimicrobial Activity