Volume 2, Issue 3 pp. 140-144
Letter

He–Ne laser (632.8 nm) pre-irradiation gives protection against DNA damage induced by a near-infrared trapping beam

Khageswar Sahu

Corresponding Author

Khageswar Sahu

Laser Biomedical Applications and Instrumentation Division, Raja Ramanna Centre for Advanced Technology, Indore-452013, India

Phone: 00-91-731-2488443, Fax: 0731-2488425Search for more papers by this author
Samarendra Kumar Mohanty

Samarendra Kumar Mohanty

Laser Biomedical Applications and Instrumentation Division, Raja Ramanna Centre for Advanced Technology, Indore-452013, India

Presently at: Beckman Laser Institute, University of California, Irvine, CA 92612, USA

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Pradeep Kumar Gupta

Pradeep Kumar Gupta

Laser Biomedical Applications and Instrumentation Division, Raja Ramanna Centre for Advanced Technology, Indore-452013, India

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First published: 09 March 2009
Citations: 11

Abstract

We report the results of a study carried out to investigate the effect of He–Ne laser (632.8 nm) pre-irradiation on DNA damage induced by continuous wave 1064 nm trapping beam exposure in MCF-7 cells. A significant decrease in % tail DNA (p < 0.05) was observed in MCF-7 cells pre-exposed to He–Ne laser beam. The dependence of the induced protection against 1064 nm trapping beam irradiation induced DNA damage on the time interval between the two irradiations as well as the He–Ne laser pre-irradiation parameters is presented. (© 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)

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