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The cover picture displays six new acorane-type sesquiterpenes penijanacoranes A—F isolated from a Mariana Trench-derived fungus Penicillium janthinellum SH0301. Penijanacorane A was a rare acorane-type sesquiterpene lactone featuring a novel 6/5/6 tricyclic system, and penijanacoranes E and F represented undescribed examples of nor-acorane sesquiterpenes at C-1. Penijanacorane C exhibited significant inhibitory activity against LPS-induced NO production in Raw264.7 macrophages. More details are discussed in the article by Wang et al. on pages 268—274.